Predicted protein targets (top 3)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CXCR4 | P61073 | 1/20 | 0.30 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.30 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8062647 | 0.96 | ALDH1A1 (0.32) | ALDH1A1 | |
| SCHEMBL8062420 | 0.91 | CXCR4 (0.30) | CXCR4SMN1; SMN2ALDH1A1 | |
| SCHEMBL8062479 | 0.89 | ALDH1A1 (0.32) | ALDH1A1 | |
| SCHEMBL477125 | 0.86 | ALDH1A1 (0.37) | SMN1; SMN2ALDH1A1 | |
| SCHEMBL477124 | 0.86 | ALDH1A1 (0.37) | SMN1; SMN2ALDH1A1 | |
| SCHEMBL8044548 | 0.86 | ALDH1A1 (0.32) | ALDH1A1 | |
| SCHEMBL477126 | 0.86 | ALDH1A1 (0.37) | SMN1; SMN2ALDH1A1 | |
| SCHEMBL8057798 | 0.85 | ALDH1A1 (0.33) | CXCR4SMN1; SMN2ALDH1A1 | |
| SCHEMBL625428 | 0.85 | ALDH1A1 (0.32) | ALDH1A1 | |
| SCHEMBL352864 | 0.82 | — | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-6140333-A | FOR TREATMENT AND/OR PROPHYLAXIS OF DISEASES INCLUDE SUCH RESPIRATORY DISEASES AS CHRONIC OBSTRUCTIVE PULMONARY DISEASES, CHRONIC BRONCHITIS, ASTHMA, CHRONIC RESPIRATORY OBSTRUCTION, PULMONARY FIBROSIS, PULMONARY EMPHYSEMA | BANYU PHARMACEUTICAL CO LTD (JP) | 2000-10-31 | — | — | US | disclosed |