Predicted protein targets (top 7)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ELANE | P08246 | 5/20 | 0.45 |
| ▸ | CMA1 | P23946 | 9/20 | 0.43 |
| ▸ | XIAP | P98170 | 1/20 | 0.42 |
| ▸ | BIRC3 | Q13489 | 1/20 | 0.42 |
| ▸ | BIRC2 | Q13490 | 1/20 | 0.42 |
| ▸ | KLK5 | Q9Y337 | 1/20 | 0.41 |
| ▸ | ACE | P12821 | 1/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL5995965 | 0.90 | ELANE (0.46) | ELANEXIAPBIRC3BIRC2 | |
| SCHEMBL12403760 | 0.90 | ELANE (0.46) | ELANEXIAPBIRC3BIRC2 | |
| SCHEMBL806133 | 0.88 | ACE (0.51) | ELANECMA1ACE | |
| SCHEMBL159043 | 0.88 | ACE (0.51) | ELANECMA1ACE | |
| SCHEMBL26121717 | 0.88 | ACE (0.51) | ELANECMA1ACE | |
| SCHEMBL15727162 | 0.88 | CMA1 (0.47) | ELANECMA1KLK5ACE | |
| SCHEMBL1300341 | 0.88 | ACE (0.51) | ELANECMA1ACE | |
| SCHEMBL24441416 | 0.87 | CMA1 (0.54) | ELANECMA1 | |
| SCHEMBL14232792 | 0.86 | ELANE (0.42) | ELANECMA1KLK5ACE | |
| SCHEMBL806180 | 0.86 | ELANE (0.42) | ELANECMA1KLK5ACE |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2012037259-A1 | NOVEL INHIBITORS OF HEPATITIS C VIRUS REPLICATION | INTERMUNE, INC. (US) | 2012-03-22 | — | — | WO | disclosed |