SCHEMBL8060622

SCHEMBL8060622

CCCCCCCC/C=C\CCCCCCCC(=O)OC(C(C)=O)C(O)CO

nearest known ligand 0.60

Predicted protein targets (top 16)

geneUniProtsupporting neighboursconfidence
PRKCA P17252 2/20 0.60
PRKCE Q02156 1/20 0.59
PRKCQ Q04759 1/20 0.59
PRKCD Q05655 1/20 0.59
DGKA P23743 1/20 0.58
FAAH O00519 3/20 0.56
MAPT P10636 2/20 0.56
CNR2 P34972 2/20 0.56
ALDH1A1 P00352 1/20 0.56
HPGD P15428 1/20 0.56
CNR1 P21554 1/20 0.56
MAPK1 P28482 1/20 0.51
DEGS1 O15121 1/20 0.51
S1PR1 P21453 1/20 0.51
DAGLA Q9Y4D2 1/20 0.48
SLC6A5 Q9Y345 1/20 0.48

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL8096475 1.00 PRKCA (0.60) PRKCAPRKCEPRKCQPRKCDDGKA
SCHEMBL10535223 0.92 MAPT (0.60) PRKCAPRKCEPRKCQPRKCDDGKA
SCHEMBL8101213 0.92 MAPT (0.60) PRKCAPRKCEPRKCQPRKCDDGKA
SCHEMBL789886 0.91 PRKCA (0.56) PRKCAPRKCEPRKCQPRKCDDGKA
SCHEMBL6269435 0.90 PRKCA (0.57) PRKCAPRKCEPRKCQPRKCDDGKA
SCHEMBL26664264 0.89 PRKCA (0.59) PRKCAPRKCEPRKCQPRKCDDGKA
SCHEMBL170318 0.89 PRKCA (0.59) PRKCAPRKCEPRKCQPRKCDDGKA
SCHEMBL27972239 0.89 PRKCA (0.59) PRKCAPRKCEPRKCQPRKCDDGKA
SCHEMBL8344879 0.89 PRKCA (0.59) PRKCAPRKCEPRKCQPRKCDDGKA
SCHEMBL27075588 0.89 PRKCA (0.59) PRKCAPRKCEPRKCQPRKCDDGKA

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-6129924-A Diglyceride and sterol based organometallic complexes and pharmaceutical compositions and dietetic products containing them MAUREL SANTE (FR) 2000-10-10 US disclosed
US-4925649-A Radioiodinated diacylglycerol analogues and methods of use THE UNIVERSITY OF MICHIGAN (US) 1990-05-15 US disclosed
EP-0279458-A1 2-Propyl amine derivatives, processes for their preparation and their use GÖDECKE AKTIENGESELLSCHAFT (DE) 1988-08-24 EP disclosed