Predicted protein targets (top 2)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TACR1 | P25103 | 1/20 | 0.30 |
| ▸ | HSD11B1 | P28845 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL12921404 | 0.82 | TACR1 (0.32) | TACR1HSD11B1 | |
| SCHEMBL12209652 | 0.80 | TACR1 (0.33) | TACR1 | |
| SCHEMBL12210740 | 0.79 | KDM4E (0.33) | TACR1 | |
| SCHEMBL12921406 | 0.79 | MAPK1 (0.32) | TACR1HSD11B1 | |
| SCHEMBL12209081 | 0.77 | IRAK4 (0.32) | HSD11B1 | |
| SCHEMBL12209504 | 0.76 | HSD11B1 (0.31) | HSD11B1 | |
| SCHEMBL375907 | 0.76 | HSD11B1 (0.31) | HSD11B1 | |
| SCHEMBL15976713 | 0.75 | TACR1 (0.32) | TACR1 | |
| SCHEMBL12209874 | 0.73 | — | — | |
| SCHEMBL8060397 | 0.71 | SLC6A4 (0.35) | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2009050248-A1 | SUBSTITUTED PIPERIDINO-DIHYDROTHIENOPYRIMIDINES | BOEHRINGER INGELHEIM INTERNATIONAL GMBH (DE) | 2009-04-23 | — | — | WO | disclosed |