Predicted protein targets (top 18)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SLC9A1 | P19634 | 10/20 | 0.65 |
| ▸ | GRM2 | Q14416 | 2/20 | 0.56 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.56 |
| ▸ | RAB9A | P51151 | 2/20 | 0.53 |
| ▸ | NPC1 | O15118 | 1/20 | 0.53 |
| ▸ | MAPT | P10636 | 1/20 | 0.53 |
| ▸ | GLA | P06280 | 1/20 | 0.51 |
| ▸ | TSHR | P16473 | 1/20 | 0.51 |
| ▸ | KCNMA1 | Q12791 | 1/20 | 0.50 |
| ▸ | KEAP1 | Q14145 | 1/20 | 0.50 |
| ▸ | EGLN3 | Q9H6Z9 | 1/20 | 0.50 |
| ▸ | APAF1 | O14727 | 1/20 | 0.50 |
| ▸ | POLB | P06746 | 1/20 | 0.50 |
| ▸ | MGAM | O43451 | 1/20 | 0.49 |
| ▸ | AMY1A | P0DUB6 | 1/20 | 0.49 |
| ▸ | GAA | P10253 | 1/20 | 0.49 |
| ▸ | SI | P14410 | 1/20 | 0.49 |
| ▸ | MGAM2 | Q2M2H8 | 1/20 | 0.49 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8203345 | 0.85 | SLC9A1 (0.63) | SLC9A1GRM2TDP1RAB9ANPC1 | |
| SCHEMBL28726870 | 0.82 | SLC9A1 (0.67) | SLC9A1GRM2RAB9ANPC1MAPT | |
| SCHEMBL29693659 | 0.81 | SLC9A1 (0.59) | SLC9A1GRM2TDP1RAB9ANPC1 | |
| SCHEMBL31067332 | 0.81 | SLC9A1 (0.59) | SLC9A1GRM2TDP1RAB9ANPC1 | |
| SCHEMBL253038 | 0.81 | SLC9A1 (0.59) | SLC9A1GRM2TDP1RAB9ANPC1 | |
| SCHEMBL8060036 | 0.81 | SLC9A1 (0.59) | SLC9A1GRM2TDP1RAB9ANPC1 | |
| SCHEMBL6039571 | 0.81 | SLC9A1 (0.59) | SLC9A1GRM2TDP1RAB9ANPC1 | |
| SCHEMBL28745839 | 0.79 | SLC9A1 (0.56) | SLC9A1GRM2TDP1RAB9ANPC1 | |
| SCHEMBL45852 | 0.79 | SLC9A1 (1.00) | SLC9A1GRM2TDP1RAB9ANPC1 | |
| SCHEMBL29735050 | 0.79 | SLC9A1 (1.00) | SLC9A1GRM2TDP1RAB9ANPC1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-6057336-A | ANTIINFLAMMATORY AGENTS | E. I. DU PONT DE NEMOURS AND COMPANY (US) | 2000-05-02 | — | — | US | disclosed |