Predicted protein targets (top 19)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PTPN1 | P18031 | 1/20 | 0.61 |
| ▸ | TNFRSF1A | P19438 | 5/20 | 0.58 |
| ▸ | ABCG2 | Q9UNQ0 | 3/20 | 0.57 |
| ▸ | ABCB1 | P08183 | 2/20 | 0.57 |
| ▸ | SMPD1 | P17405 | 1/20 | 0.57 |
| ▸ | HDAC1 | Q13547 | 1/20 | 0.57 |
| ▸ | HDAC8 | Q9BY41 | 1/20 | 0.57 |
| ▸ | HDAC6 | Q9UBN7 | 1/20 | 0.57 |
| ▸ | NPC1 | O15118 | 1/20 | 0.55 |
| ▸ | HPGD | P15428 | 1/20 | 0.55 |
| ▸ | RAB9A | P51151 | 1/20 | 0.55 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.55 |
| ▸ | PDE4A | P27815 | 1/20 | 0.53 |
| ▸ | PDE4B | Q07343 | 1/20 | 0.53 |
| ▸ | PDE4C | Q08493 | 1/20 | 0.53 |
| ▸ | PDE4D | Q08499 | 1/20 | 0.53 |
| ▸ | SNCA | P37840 | 1/20 | 0.52 |
| ▸ | PTGER4 | P35408 | 1/20 | 0.52 |
| ▸ | PTGER2 | P43116 | 1/20 | 0.52 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8064357 | 0.92 | PTPN1 (0.54) | PTPN1TNFRSF1AABCG2ABCB1SMPD1 | |
| SCHEMBL16246459 | 0.85 | TNFRSF1A (0.76) | TNFRSF1AABCG2ABCB1SMPD1HDAC1 | |
| SCHEMBL16246460 | 0.85 | TNFRSF1A (0.76) | TNFRSF1AABCG2ABCB1SMPD1HDAC1 | |
| SCHEMBL8052867 | 0.84 | TNFRSF1A (0.58) | PTPN1TNFRSF1AABCG2ABCB1SMPD1 | |
| SCHEMBL8064254 | 0.84 | TNFRSF1A (0.55) | PTPN1TNFRSF1AABCG2SMPD1HDAC1 | |
| SCHEMBL8064252 | 0.84 | TNFRSF1A (0.55) | PTPN1TNFRSF1AABCG2SMPD1HDAC1 | |
| SCHEMBL25301594 | 0.83 | APP (0.70) | TNFRSF1AABCG2NPC1HPGDRAB9A | |
| SCHEMBL8064391 | 0.83 | PTPN1 (0.56) | PTPN1TNFRSF1AABCG2SMPD1HDAC1 | |
| SCHEMBL21643517 | 0.83 | PDE4A (0.67) | TNFRSF1AABCG2NPC1HPGDRAB9A | |
| SCHEMBL29803332 | 0.83 | PDE4A (0.67) | TNFRSF1AABCG2NPC1HPGDRAB9A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-6025387-A | Gastroprotective flavone/flavanone compounds with therapeutic effect on inflammatory bowel disease | DONG A PHARMACEUTICAL CO., LTD. (KR) | 2000-02-15 | — | — | US | disclosed |