Predicted protein targets (top 18)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MEN1 | O00255 | 1/20 | 0.57 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.57 |
| ▸ | EPHX2 | P34913 | 2/20 | 0.53 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.47 |
| ▸ | CASP2 | P42575 | 1/20 | 0.44 |
| ▸ | NAAA | Q02083 | 1/20 | 0.42 |
| ▸ | MAOA | P21397 | 1/20 | 0.42 |
| ▸ | MAOB | P27338 | 1/20 | 0.42 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.41 |
| ▸ | GAA | P10253 | 1/20 | 0.41 |
| ▸ | FAAH | O00519 | 2/20 | 0.40 |
| ▸ | RECQL | P46063 | 1/20 | 0.40 |
| ▸ | CA12 | O43570 | 1/20 | 0.39 |
| ▸ | CA1 | P00915 | 1/20 | 0.39 |
| ▸ | CA2 | P00918 | 1/20 | 0.39 |
| ▸ | CA9 | Q16790 | 1/20 | 0.39 |
| ▸ | HDAC8 | Q9BY41 | 1/20 | 0.39 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL540944 | 0.87 | CASP2 (0.59) | MEN1KMT2AEPHX2CASP2NAAA | |
| SCHEMBL17751908 | 0.87 | CASP2 (0.59) | MEN1KMT2AEPHX2CASP2NAAA | |
| SCHEMBL1709282 | 0.86 | MEN1 (0.48) | MEN1KMT2AEPHX2TDP1GAA | |
| SCHEMBL24894495 | 0.86 | CASP2 (0.57) | EPHX2CASP2NAAAL3MBTL1FAAH | |
| SCHEMBL20556419 | 0.84 | EPHX2 (0.51) | MEN1KMT2AEPHX2TDP1CASP2 | |
| SCHEMBL16863818 | 0.84 | EPHX2 (0.51) | MEN1KMT2AEPHX2TDP1CASP2 | |
| SCHEMBL29177627 | 0.83 | EPHX2 (0.50) | MEN1KMT2AEPHX2TDP1CASP2 | |
| SCHEMBL22473805 | 0.83 | TDP1 (0.69) | MEN1KMT2ATDP1CASP2MAOA | |
| SCHEMBL30111127 | 0.83 | EPHX2 (0.49) | EPHX2TDP1CASP2L3MBTL1GAA | |
| SCHEMBL25942884 | 0.83 | TDP1 (0.69) | MEN1KMT2AEPHX2TDP1MAOA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2012037254-A1 | MODIFIED iRNA AGENTS | ALNYLAM PHARMACEUTICALS, INC. (US) | 2012-03-22 | — | — | WO | disclosed |