Predicted protein targets (top 15)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PDE4B | Q07343 | 3/20 | 0.63 |
| ▸ | PDE4D | Q08499 | 2/20 | 0.41 |
| ▸ | TAAR1 | Q96RJ0 | 2/20 | 0.39 |
| ▸ | MAOB | P27338 | 2/20 | 0.36 |
| ▸ | F11 | P03951 | 1/20 | 0.35 |
| ▸ | TDO2 | P48775 | 1/20 | 0.35 |
| ▸ | SLC6A9 | P48067 | 1/20 | 0.34 |
| ▸ | BACE1 | P56817 | 1/20 | 0.34 |
| ▸ | FAAH | O00519 | 2/20 | 0.33 |
| ▸ | PDE4A | P27815 | 1/20 | 0.33 |
| ▸ | MEN1 | O00255 | 1/20 | 0.33 |
| ▸ | POLB | P06746 | 1/20 | 0.33 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.33 |
| ▸ | CYP19A1 | P11511 | 1/20 | 0.33 |
| ▸ | PTGDR2 | Q9Y5Y4 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL3790138 | 0.86 | PDE4B (0.63) | PDE4BPDE4DTAAR1MAOBF11 | |
| SCHEMBL3465815 | 0.86 | PDE4B (0.63) | PDE4BPDE4DTAAR1F11SLC6A9 | |
| SCHEMBL31297174 | 0.83 | PDE4B (0.59) | PDE4BPDE4DTAAR1PDE4AMEN1 | |
| SCHEMBL8069736 | 0.82 | PDE4B (0.60) | PDE4BPDE4DTAAR1 | |
| SCHEMBL3796788 | 0.78 | PDE4B (0.54) | PDE4BPDE4DF11SLC6A9FAAH | |
| SCHEMBL3466495 | 0.78 | PDE4B (0.54) | PDE4BPDE4DTAAR1F11TDO2 | |
| SCHEMBL15195923 | 0.78 | PDE4B (0.53) | PDE4BPDE4DF11TDO2BACE1 | |
| SCHEMBL7911270 | 0.78 | PDE4B (0.53) | PDE4BPDE4DTAAR1F11TDO2 | |
| Hydrochloric Acid SCHEMBL3788377 | 0.77 | PDE4B (0.53) | PDE4BPDE4DTAAR1MAOBF11 | |
| SCHEMBL31297173 | 0.77 | PDE4B (0.53) | PDE4BPDE4DTAAR1F11BACE1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2009067600-A2 | BIARYL PDE4 INHIBITORS FOR TREATING INFLAMMATION | DECODE GENETICS EHF (IS) | 2009-05-28 | — | — | WO | disclosed |