Predicted protein targets (top 11)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TYR | P14679 | 5/20 | 0.50 |
| ▸ | MEN1 | O00255 | 1/20 | 0.38 |
| ▸ | TP53 | P04637 | 1/20 | 0.38 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.38 |
| ▸ | ALOX5 | P09917 | 1/20 | 0.38 |
| ▸ | MAPT | P10636 | 1/20 | 0.38 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.38 |
| ▸ | TSHR | P16473 | 1/20 | 0.38 |
| ▸ | HTT | P42858 | 1/20 | 0.38 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.38 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8059449 | 0.90 | TYR (0.50) | TYRMEN1TP53CYP3A4ALOX5 | |
| SCHEMBL8063175 | 0.87 | TYR (0.58) | TYRMEN1TP53CYP3A4ALOX5 | |
| SCHEMBL7796595 | 0.78 | CA1 (0.35) | TP53CYP3A4ALOX5MAPTALOX15 | |
| SCHEMBL8060984 | 0.76 | TYR (0.50) | TYRMEN1TP53CYP3A4ALOX5 | |
| SCHEMBL8060740 | 0.74 | TYR (0.50) | TYRMEN1TP53CYP3A4ALOX5 | |
| SCHEMBL7794918 | 0.72 | POLB (0.49) | — | |
| SCHEMBL8385360 | 0.71 | GAA (0.35) | TYRMEN1CYP3A4MAPTKMT2A | |
| SCHEMBL2967602 | 0.70 | TSHR (0.58) | TYRCYP3A4TSHR | |
| SCHEMBL7786646 | 0.70 | POLB (0.49) | — | |
| SCHEMBL16309507 | 0.69 | TYR (0.54) | TYRMEN1TP53CYP3A4ALOX5 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-6093836-A | INHIBITORY ACTIVITY AGAINT MELANIN BIOSYNTHESIS; WHITENING SUBSTANCES FOR MEDICAMENTS, COSMETICS | LG CHEMICAL LTD. (KR) | 2000-07-25 | — | — | US | disclosed |
| EP-0909267-A1 | NOVEL 1,3-DIPHENYLPROPANE DERIVATIVES HAVING INHIBITORY ACTIVITY AGAINST TYROSINASE AND PROCESS FOR PREPARATION THEREOF | LG CHEMICAL LIMITED (KR) | 1999-04-21 | — | — | EP | disclosed |
| WO-1998039279-A1 | NOVEL 1,3-DIPHENYLPROPANE DERIVATIVES HAVING INHIBITORY ACTIVITY AGAINST TYROSINASE AND PROCESS FOR PREPARATION THEREOF | LG CHEMICAL LTD. (KR) | 1998-09-11 | — | — | WO | disclosed |