Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CA1 | P00915 | 1/20 | 0.35 |
| ▸ | CA2 | P00918 | 1/20 | 0.35 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.33 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.33 |
| ▸ | LMNA | P02545 | 1/20 | 0.33 |
| ▸ | TP53 | P04637 | 1/20 | 0.33 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.33 |
| ▸ | MAPT | P10636 | 1/20 | 0.33 |
| ▸ | HPGD | P15428 | 1/20 | 0.33 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.33 |
| ▸ | ALOX12 | P18054 | 1/20 | 0.33 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.33 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.33 |
| ▸ | PTGS2 | P35354 | 1/20 | 0.32 |
| ▸ | ADRA1D | P25100 | 1/20 | 0.31 |
| ▸ | ADRA1A | P35348 | 1/20 | 0.31 |
| ▸ | ADRA1B | P35368 | 1/20 | 0.31 |
| ▸ | PABPC1 | P11940 | 1/20 | 0.31 |
| ▸ | IMPDH2 | P12268 | 2/20 | 0.30 |
| ▸ | IMPDH1 | P20839 | 2/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7796094 | 0.89 | CA1 (0.35) | CA1CA2KDM4EALDH1A1LMNA | |
| SCHEMBL7792441 | 0.86 | TRPA1 (0.33) | CA1CA2ALDH1A1LMNAHPGD | |
| SCHEMBL7786650 | 0.79 | GAA (0.33) | CA1CA2KDM4EALDH1A1MAPT | |
| SCHEMBL8063169 | 0.78 | TYR (0.50) | TP53CYP3A4MAPTALOX15ALOX5 | |
| SCHEMBL7792520 | 0.77 | CA1 (0.40) | CA1CA2KDM4EALDH1A1LMNA | |
| SCHEMBL7786624 | 0.74 | CA1 (0.40) | CA1CA2KDM4EALDH1A1LMNA | |
| SCHEMBL8059449 | 0.68 | TYR (0.50) | TP53CYP3A4MAPTALOX15ALOX5 | |
| SCHEMBL10735633 | 0.66 | PTAFR (0.39) | ALDH1A1 | |
| SCHEMBL7795026 | 0.66 | TRPA1 (0.40) | CA1CA2KDM4EALDH1A1LMNA | |
| SCHEMBL22070808 | 0.65 | CA12 (0.50) | CA1CA2ALDH1A1MAPTHPGD |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0909267-B1 | NOVEL 1,3-DIPHENYLPROPANE DERIVATIVES HAVING INHIBITORY ACTIVITY AGAINST TYROSINASE AND PROCESS FOR PREPARATION THEREOF | LG CHEMICAL LTD (KR) | 2001-11-21 | — | — | EP | disclosed |