SCHEMBL8063191

SCHEMBL8063191

CCCCC(Cl)CCCCl

nearest known ligand 0.56

Predicted protein targets (top 13)

geneUniProtsupporting neighboursconfidence
TSHR P16473 7/20 0.56
TDP1 Q9NUW8 3/20 0.56
ALDH1A1 P00352 5/20 0.50
DNM1 Q05193 2/20 0.39
SMN1; SMN2 Q16637 1/20 0.33
CYP3A4 P08684 1/20 0.33
LMNA P02545 1/20 0.33
FDPS P14324 1/20 0.33
CA2 P00918 2/20 0.32
MAPK1 P28482 1/20 0.32
OPRM1 P35372 1/20 0.32
THRB P10828 1/20 0.32
CA1 P00915 1/20 0.31

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL18107310 0.95 TSHR (0.52) TSHRTDP1ALDH1A1DNM1SMN1; SMN2
SCHEMBL29173026 0.92 TSHR (0.57) TSHRTDP1ALDH1A1DNM1LMNA
SCHEMBL28999212 0.92 TSHR (0.55) TSHRTDP1ALDH1A1DNM1LMNA
SCHEMBL10179625 0.92
SCHEMBL4540450 0.91 DNM1 (0.45) TSHRTDP1ALDH1A1DNM1SMN1; SMN2
SCHEMBL28999276 0.90 TSHR (0.48) TSHRTDP1ALDH1A1DNM1LMNA
SCHEMBL28993072 0.90 TSHR (0.62) TSHRTDP1ALDH1A1DNM1LMNA
SCHEMBL6764168 0.89 TSHR (0.60) TSHRTDP1ALDH1A1DNM1LMNA
SCHEMBL18107404 0.89 TSHR (0.43) TSHRTDP1ALDH1A1DNM1SMN1; SMN2
SCHEMBL1784504 0.88

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 10 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-119219840-A Crosslinked polymer and preparation method and application thereof 中国石油化工股份有限公司 2024-12-31 CN disclosed
CN-119219824-A Crosslinked polymer and preparation method and application thereof 中国石油化工股份有限公司 2024-12-31 CN disclosed
CN-116063345-B Phosphonic acid group monomer and preparation method thereof 中国石油化工股份有限公司 2024-08-06 CN disclosed
CN-116063626-B Anti-calcium shrinkage and expansion agent and preparation method and application thereof 中国石油化工股份有限公司 2024-05-07 CN disclosed
CN-116064016-B Scale inhibition anti-swelling shrinkage swelling agent and preparation method and application thereof 中国石油化工股份有限公司 2024-04-05 CN disclosed
CN-116064016-A Scale inhibition anti-swelling shrinkage swelling agent and preparation method and application thereof 中国石油化工股份有限公司 2023-05-05 CN disclosed
CN-116063626-A Anti-calcium shrinkage and expansion agent and preparation method and application thereof 中国石油化工股份有限公司 2023-05-05 CN disclosed
US-6096680-A REUSABLE ALUMINUM FRIEDEL-CRAFTS CATALYSTS; FORMED FROM AN ALUMINUM TRIHALIDE, ALKALI METAL HALIDE OR PSEUDOHALIDE, ALKALINE EARTH METAL HALIDE, QUATERNARY AMMONIUM, PHOSPHONIUM AND/OR SULFONIUM SALT AND AN AROMATIC HYDROCARBON ALBEMARLE CORPORATION (US) 2000-08-01 US disclosed
US-5859302-A Processes employing reusable aluminum catalysts ALBEMARLE CORPORATION (US) 1999-01-12 US disclosed
EP-0838447-A1 Processes employing reusable aluminum catalysts ALBEMARLE CORPORATION (US) 1998-04-29 EP disclosed