SCHEMBL8063408

SCHEMBL8063408

CC(CO)COC(=O)c1ccc(C(=O)O)cc1

nearest known ligand 0.76

Predicted protein targets (top 17)

geneUniProtsupporting neighboursconfidence
MAPT P10636 1/20 0.76
ALDH1A1 P00352 3/20 0.47
ADRB2 P07550 8/20 0.46
ADRB1 P08588 8/20 0.46
ADRB3 P13945 8/20 0.46
KMT2A Q03164 1/20 0.44
SLC1A5 Q15758 1/20 0.43
MAPK1 P28482 1/20 0.42
PRKCA P17252 1/20 0.42
TP53 P04637 1/20 0.41
TSHR P16473 1/20 0.41
ACHE P22303 1/20 0.41
PLA2G1B P04054 1/20 0.41
ATG4B Q9Y4P1 1/20 0.41
NPC1 O15118 1/20 0.41
HTT P42858 1/20 0.41
RAB9A P51151 1/20 0.41

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL7771559 0.93 MAPT (0.64) MAPTALDH1A1ADRB2ADRB1ADRB3
SCHEMBL11146237 0.91 MAPT (0.83) MAPTALDH1A1ADRB2ADRB1ADRB3
SCHEMBL5153013 0.88 ALDH1A1 (0.62) MAPTALDH1A1ADRB2ADRB1ADRB3
SCHEMBL6558576 0.86 MAPT (0.58) MAPTALDH1A1ADRB2ADRB1ADRB3
SCHEMBL9345539 0.86 MAPT (1.00) MAPTALDH1A1ADRB2ADRB1ADRB3
SCHEMBL9345545 0.86 MAPT (1.00) MAPTALDH1A1ADRB2ADRB1ADRB3
SCHEMBL29096681 0.85 MAPT (0.97) MAPTALDH1A1ADRB2ADRB1ADRB3
SCHEMBL2819868 0.84 MAPT (0.55) MAPTALDH1A1ADRB2ADRB1ADRB3
SCHEMBL208053 0.84 MAPT (0.72) MAPTALDH1A1ADRB2ADRB1ADRB3
SCHEMBL27103108 0.83 MAPT (0.77) MAPTALDH1A1ADRB2ADRB1ADRB3

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 9 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-106008945-B Preparation method of polyester 苏州大学 2018-07-03 CN disclosed
CN-106008945-A Preparation method of polyester 苏州大学 2016-10-12 CN disclosed
CN-101765638-B Polyester polycarbonate compositions, methods of making, and articles formed therefrom SABIC INNOVATIVE PLASTICS IP 2013-10-23 CN disclosed
CN-101765638-A Polyester polycarbonate compositions, methods of making, and articles formed therefrom SABIC INNOVATIVE PLASTICS IP 2010-06-30 CN disclosed
CN-101688053-A Polyester polycarbonate composition, its preparation method and by its goods that form SABIC INNOVATIVE PLASTICS IP 2010-03-31 CN disclosed
EP-1009777-A1 POLYESTER TONER COMPOSITION FOR ELECTROPHOTOGRAPHIC IMAGING SYSTEMS Ticona LLC (US) 2000-06-21 EP disclosed
US-5932666-A REACTING RECYCLED POLYETHYLENE TEREPHTHALATE WITH 1,3-BUTANEDIOL OR DIETHYLENE GLYCOL AND ALIPHATIC DIACID ASHLAND INC. (US) 1999-08-03 US disclosed
WO-1999011720-A1 POLYESTER TONER COMPOSITION FOR ELECTROPHOTOGRAPHIC IMAGING SYSTEMS TICONA LLC (US) 1999-03-11 WO disclosed
US-5756554-A Low profile additives for polyester resin systems based on asymmetric glycols and aromatic diacids ASHLAND INC. (US) 1998-05-26 US disclosed