Predicted protein targets (top 3)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HSD17B7 | P56937 | 2/20 | 0.59 |
| ▸ | SRD5A1 | P18405 | 8/20 | 0.58 |
| ▸ | SRD5A2 | P31213 | 2/20 | 0.56 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8071947 | 1.00 | HSD17B7 (0.59) | HSD17B7SRD5A1SRD5A2 | |
| SCHEMBL8078855 | 1.00 | HSD17B7 (0.59) | HSD17B7SRD5A1SRD5A2 | |
| SCHEMBL8063800 | 0.93 | SRD5A1 (0.57) | SRD5A1SRD5A2 | |
| SCHEMBL8926391 | 0.86 | HSD17B7 (0.54) | HSD17B7SRD5A1SRD5A2 | |
| SCHEMBL11140279 | 0.84 | SRD5A1 (0.64) | HSD17B7SRD5A1SRD5A2 | |
| SCHEMBL8072501 | 0.83 | SRD5A2 (0.61) | SRD5A2 | |
| SCHEMBL8071815 | 0.83 | SRD5A2 (0.61) | SRD5A1SRD5A2 | |
| SCHEMBL8064050 | 0.83 | SRD5A2 (0.61) | SRD5A1SRD5A2 | |
| SCHEMBL9113835 | 0.83 | SRD5A2 (0.61) | SRD5A2 | |
| SCHEMBL8064047 | 0.83 | SRD5A2 (0.61) | SRD5A1SRD5A2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 7 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0641208-B1 | 4-AZASTEROID 5-ALPHA-REDUCTASE INHIBITORS | MERCK & CO INC (US) | 2000-08-02 | — | — | EP | claimed |
| US-5620986-A | TREATS BENIGN PROSTATIC HYPERTROPHY, SEBORRHEA, FEMALE HIRSUTISM, AND MALE AND FEMALE PATTEN BALDNESS | MERCK & CO., INC. (US) | 1997-04-15 | — | — | US | claimed |
| EP-0641208-A4 | 4-AZASTEROID 5-ALPHA-REDUCTASE INHIBITORS. | MERCK & CO INC (US) | 1995-08-30 | — | — | EP | claimed |
| EP-0641208-A1 | 4-AZASTEROID 5-ALPHA-REDUCTASE INHIBITORS | MERCK & CO. INC. (US) | 1995-03-08 | — | — | EP | claimed |
| EP-0641208-B1 | 4-AZASTEROID 5-ALPHA-REDUCTASE INHIBITORS | MERCK & CO INC (US) | 2000-08-02 | — | — | EP | disclosed |
| US-5693809-A | PREGNANES FOR TREATING ALOPECIA, ACNE AND SKIN DISORDER | MERCK & CO., INC. (US) | 1997-12-02 | — | — | US | disclosed |
| US-5620986-A | TREATS BENIGN PROSTATIC HYPERTROPHY, SEBORRHEA, FEMALE HIRSUTISM, AND MALE AND FEMALE PATTEN BALDNESS | MERCK & CO., INC. (US) | 1997-04-15 | — | — | US | disclosed |