Predicted protein targets (top 12)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | AVPR1B | P47901 | 5/20 | 0.40 |
| ▸ | F2 | P00734 | 1/20 | 0.39 |
| ▸ | AVPR1A | P37288 | 4/20 | 0.38 |
| ▸ | PLG | P00747 | 1/20 | 0.35 |
| ▸ | NPY4R | P50391 | 2/20 | 0.35 |
| ▸ | NPY1R | P25929 | 1/20 | 0.35 |
| ▸ | EPHX2 | P34913 | 1/20 | 0.34 |
| ▸ | NMT1 | P30419 | 2/20 | 0.33 |
| ▸ | MEN1 | O00255 | 1/20 | 0.33 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.33 |
| ▸ | RXFP1 | Q9HBX9 | 1/20 | 0.33 |
| ▸ | MARS1 | P56192 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL30038580 | 0.80 | AVPR1B (0.43) | AVPR1BF2AVPR1APLGNMT1 | |
| SCHEMBL24136539 | 0.80 | AVPR1B (0.43) | AVPR1BF2AVPR1APLGNMT1 | |
| SCHEMBL22139318 | 0.80 | AVPR1B (0.43) | AVPR1BF2AVPR1APLGNMT1 | |
| SCHEMBL9329697 | 0.79 | AVPR1B (0.52) | AVPR1BF2AVPR1APLG | |
| SCHEMBL4901697 | 0.78 | AVPR1B (0.42) | AVPR1BF2AVPR1APLGNMT1 | |
| SCHEMBL7898282 | 0.78 | AVPR1B (0.54) | AVPR1BF2AVPR1APLG | |
| SCHEMBL1509780 | 0.78 | AVPR1B (0.54) | AVPR1BF2AVPR1APLG | |
| SCHEMBL30007346 | 0.78 | AVPR1B (0.54) | AVPR1BF2AVPR1APLG | |
| SCHEMBL1509781 | 0.78 | AVPR1B (0.54) | AVPR1BF2AVPR1APLG | |
| Hydrochloric Acid SCHEMBL4901689 | 0.78 | AVPR1B (0.42) | AVPR1BF2AVPR1APLGNMT1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0643778-B1 | ENCODED COMBINATORIAL CHEMICAL LIBRARIES | SCRIPPS RESEARCH INST (US) | 2000-05-31 | — | — | EP | disclosed |
| EP-0643778-A4 | ENCODED COMBINATORIAL CHEMICAL LIBRARIES. | SCRIPPS RESEARCH INST (US) | 1995-09-20 | — | — | EP | disclosed |
| EP-0643778-A1 | ENCODED COMBINATORIAL CHEMICAL LIBRARIES | THE SCRIPPS RESEARCH INSTITUTE (US) | 1995-03-22 | — | — | EP | disclosed |
| WO-1993020242-A1 | ENCODED COMBINATORIAL CHEMICAL LIBRARIES | THE SCRIPPS RESEARCH INSTITUTE (US) | 1993-10-14 | — | — | WO | disclosed |