SCHEMBL8064466

SCHEMBL8064466

C1=Cc2nc3ccccc3nc2CC1.CN1c2ccccc2N(C)c2ccccc21

nearest known ligand 0.31

Predicted protein targets (top 3)

geneUniProtsupporting neighboursconfidence
HRH4 Q9H3N8 1/20 0.31
ACHE P22303 1/20 0.30
MAOA P21397 1/20 0.30

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL38102 0.87 MAPT (0.39) ACHE
SCHEMBL7168253 0.85 MAPT (0.37) ACHE
SCHEMBL7168251 0.85 MAPT (0.37) ACHE
SCHEMBL5347514 0.81 NQO2 (0.41) ACHE
Oxirane SCHEMBL3048492 0.81 POLB (0.36)
Hydrochloric Acid SCHEMBL5348406 0.80 NQO2 (0.39) ACHE
Pyrene SCHEMBL28979821 0.78 CYP1A2 (0.35) ACHEMAOA
SCHEMBL18560548 0.77 BCHE (0.38) ACHE
Anthraquinone SCHEMBL28662821 0.77 RAB9A (0.42) ACHEMAOA
SCHEMBL29213640 0.76 MAPT (0.34)

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-6141137-A Electrochromic media for producing a preselected color GENTEX CORPORATION (US) 2000-10-31 US disclosed