Predicted protein targets (top 5)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HSD17B1 | P14061 | 4/20 | 0.37 |
| ▸ | LMNA | P02545 | 1/20 | 0.31 |
| ▸ | HPGD | P15428 | 1/20 | 0.31 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.31 |
| ▸ | HTT | P42858 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4858324 | 0.82 | CYP3A4 (0.33) | HSD17B1HSD17B10 | |
| SCHEMBL27876071 | 0.81 | TUBB1 (0.38) | LMNAHPGD | |
| SCHEMBL8066042 | 0.76 | HSD17B1 (0.33) | HSD17B1 | |
| SCHEMBL8088779 | 0.75 | MCL1 (0.44) | — | |
| SCHEMBL10916725 | 0.75 | HSD17B1 (0.45) | HSD17B1 | |
| SCHEMBL11466692 | 0.75 | MCL1 (0.37) | HPGD | |
| SCHEMBL7468946 | 0.75 | CYP11B1 (0.42) | LMNAHPGD | |
| SCHEMBL8079296 | 0.74 | HSD17B1 (0.41) | HSD17B1 | |
| SCHEMBL3143778 | 0.74 | PDGFRB (0.37) | — | |
| SCHEMBL27791379 | 0.74 | MAPK1 (0.35) | LMNAHPGDHSD17B10 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-6166072-A | Amino acid derivatives | ALLELIX NEUROSCIENCE, INC. (CA) | 2000-12-26 | — | — | US | disclosed |