SCHEMBL8064768

SCHEMBL8064768

COc1cc(O)cc(OC)c1-c1c(OC)cc(O)cc1OC

nearest known ligand 0.67

Predicted protein targets (top 19)

geneUniProtsupporting neighboursconfidence
CYP3A4 P08684 1/20 0.67
MAPT P10636 1/20 0.67
PTGS2 P35354 6/20 0.56
ALOX5 P09917 5/20 0.56
MAOB P27338 1/20 0.54
TDP1 Q9NUW8 1/20 0.48
MGAM O43451 2/20 0.45
GAA P10253 2/20 0.45
SI P14410 2/20 0.45
MGAM2 Q2M2H8 2/20 0.45
CYP1A1 P04798 1/20 0.43
PTGS1 P23219 1/20 0.43
ESR1 P03372 2/20 0.43
ESR2 Q92731 2/20 0.43
TTR P02766 1/20 0.42
APP P05067 1/20 0.42
SYNJ2 O15056 1/20 0.41
HIF1A Q16665 1/20 0.41
PTPN1 P18031 1/20 0.41

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL14007407 0.90 CYP3A4 (0.56) CYP3A4MAPTPTGS2ALOX5MAOB
SCHEMBL70379 0.82 ALOX5 (0.70) CYP3A4MAPTPTGS2ALOX5MAOB
SCHEMBL11498857 0.81 MGAM (0.65) CYP3A4MAPTMAOBMGAMGAA
Ethane SCHEMBL27660205 0.80 ALOX5 (0.67) CYP3A4MAPTPTGS2ALOX5MAOB
Antiarol SCHEMBL210578 0.80 CYP3A4 (1.00) CYP3A4MAPTPTGS2ALOX5MAOB
SCHEMBL320899 0.80 CYP3A4 (0.64) CYP3A4MAPTPTGS2ALOX5MAOB
SCHEMBL10676347 0.79 PDE4B (0.52) CYP3A4MAPTPTGS2ALOX5MAOB
SCHEMBL28273207 0.79 CYP3A4 (0.52) CYP3A4MAPTPTGS2MAOBTDP1
Water SCHEMBL11498856 0.79 MGAM (0.62) CYP3A4MAPTMAOBMGAMGAA
SCHEMBL23757778 0.78 CYP3A4 (0.61) CYP3A4MAPTPTGS2ALOX5MAOB

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 10 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-111530311-B Preparation method of monolithic poly (arylene ether nitrile) bipolar membrane containing corrole water dissociation catalytic group 福建师范大学 2022-03-15 CN disclosed
CN-111530298-B Preparation method of monolithic polyarylethersulfone ketone bipolar membrane containing phthalocyanine water dissociation catalytic group 福建师范大学 2021-11-23 CN disclosed
CN-111530298-A Preparation method of monolithic polyarylethersulfone ketone bipolar membrane containing phthalocyanine water dissociation catalytic group 福建师范大学 2020-08-14 CN disclosed
CN-111530311-A Preparation method of monolithic poly (arylene ether nitrile) bipolar membrane containing corrole water dissociation catalytic group 福建师范大学 2020-08-14 CN disclosed
CN-106699520-A Method for synthesizing 3,3',5,5'-tetramethoxyl-4,4'-biphenol 甘肃省化工研究院 2017-05-24 CN disclosed
CN-106699520-A Method for synthesizing 3,3',5,5'-tetramethoxyl-4,4'-biphenol 甘肃省化工研究院 2017-05-24 CN disclosed
US-20080280994-A1 Ascophyllum Compositions and Methods OCEAN NUTRITION CANDA LTD. 2008-11-13 US disclosed
US-20080280994-A1 Ascophyllum Compositions and Methods OCEAN NUTRITION CANDA LTD. 2008-11-13 US disclosed
US-6077928-A Bis(dialkylmaleimide) derivative and polyetherimide for optical communications formed therefrom SAMSUNG ELECTRONICS CO., LTD. (KR) 2000-06-20 US disclosed
US-6031061-A Bis (triaklyltrimellitic anhydride) derivative and polyesterimide for optical communications formed therefrom SAMSUNG ELECTRONICS CO., LTD. (KR) 2000-02-29 US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20080280994-A1 Ascophyllum Compositions and Methods GANAB, GBA3, GANC CYP3A4 1861/4885MAPT 2678/4885PTGS2 513/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.