SCHEMBL8064922

SCHEMBL8064922

COc1ccc2cc(-c3cccc(N)c3)cc(CCNC(C)=S)c2c1

nearest known ligand 0.81

Predicted protein targets (top 2)

geneUniProtsupporting neighboursconfidence
MTNR1A P48039 20/20 0.81
MTNR1B P49286 19/20 0.81

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL8065619 0.91 MTNR1A (0.67) MTNR1AMTNR1B
SCHEMBL6246703 0.90 MTNR1A (1.00) MTNR1AMTNR1B
Hydrochloric Acid SCHEMBL6248348 0.89 MTNR1A (0.98) MTNR1AMTNR1B
SCHEMBL8065683 0.88 MTNR1A (0.79) MTNR1AMTNR1B
SCHEMBL6247009 0.81 MTNR1A (0.85) MTNR1AMTNR1B
SCHEMBL6247158 0.79 MTNR1A (0.78) MTNR1AMTNR1B
SCHEMBL8054025 0.79 MTNR1A (0.57) MTNR1AMTNR1B
SCHEMBL5929485 0.78 MTNR1A (1.00) MTNR1AMTNR1B
SCHEMBL6250308 0.78 MTNR1A (0.80) MTNR1AMTNR1B
SCHEMBL6247733 0.77 MTNR1A (1.00) MTNR1AMTNR1B

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-6143789-A ENANTIOMORPHS ADIR ET COMPAGNIE (FR) 2000-11-07 US disclosed
EP-0919541-A1 Naphthalene compounds, process for their preparation and their pharmaceutical compositions ADIR ET COMPAGNIE (FR) 1999-06-02 EP disclosed