Predicted protein targets (top 4)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MTNR1A | P48039 | 19/20 | 0.64 |
| ▸ | MTNR1B | P49286 | 17/20 | 0.64 |
| ▸ | NQO2 | P16083 | 14/20 | 0.64 |
| ▸ | HTR2C | P28335 | 1/20 | 0.50 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8054181 | 0.86 | MTNR1A (0.58) | MTNR1AMTNR1BNQO2HTR2C | |
| SCHEMBL8065694 | 0.84 | MTNR1A (0.58) | MTNR1AMTNR1BNQO2HTR2C | |
| SCHEMBL15346396 | 0.81 | MTNR1A (0.65) | MTNR1AMTNR1BNQO2HTR2C | |
| SCHEMBL4260242 | 0.79 | MTNR1A (0.65) | MTNR1AMTNR1BNQO2HTR2C | |
| SCHEMBL6245857 | 0.78 | MTNR1A (0.77) | MTNR1AMTNR1BNQO2HTR2C | |
| SCHEMBL8886469 | 0.78 | MTNR1A (0.82) | MTNR1AMTNR1BNQO2HTR2C | |
| SCHEMBL4685396 | 0.78 | MTNR1A (1.00) | MTNR1AMTNR1BNQO2HTR2C | |
| SCHEMBL4685402 | 0.78 | MTNR1A (1.00) | MTNR1AMTNR1BNQO2HTR2C | |
| SCHEMBL7950293 | 0.78 | MTNR1A (1.00) | MTNR1AMTNR1BNQO2HTR2C | |
| SCHEMBL7950130 | 0.76 | MTNR1A (0.86) | MTNR1AMTNR1BNQO2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-6143789-A | ENANTIOMORPHS | ADIR ET COMPAGNIE (FR) | 2000-11-07 | — | — | US | disclosed |
| EP-0919541-A1 | Naphthalene compounds, process for their preparation and their pharmaceutical compositions | ADIR ET COMPAGNIE (FR) | 1999-06-02 | — | — | EP | disclosed |