Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | POLB | P06746 | 2/20 | 0.42 |
| ▸ | MAPT | P10636 | 3/20 | 0.41 |
| ▸ | NPC1 | O15118 | 1/20 | 0.41 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.41 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.41 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.41 |
| ▸ | HPGD | P15428 | 1/20 | 0.41 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.41 |
| ▸ | RAB9A | P51151 | 1/20 | 0.41 |
| ▸ | CYP19A1 | P11511 | 1/20 | 0.38 |
| ▸ | CYP11B1 | P15538 | 1/20 | 0.38 |
| ▸ | CYP11B2 | P19099 | 1/20 | 0.38 |
| ▸ | HTT | P42858 | 1/20 | 0.37 |
| ▸ | KDM4E | B2RXH2 | 4/20 | 0.36 |
| ▸ | NPSR1 | Q6W5P4 | 2/20 | 0.36 |
| ▸ | GAA | P10253 | 1/20 | 0.36 |
| ▸ | MAOA | P21397 | 1/20 | 0.35 |
| ▸ | MAOB | P27338 | 1/20 | 0.35 |
| ▸ | MEN1 | O00255 | 1/20 | 0.35 |
| ▸ | TSHR | P16473 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL26022905 | 0.88 | MAPT (0.42) | POLBMAPTNPC1CYP1A2CYP3A4 | |
| SCHEMBL29428465 | 0.87 | MAPT (0.43) | POLBMAPTNPC1CYP1A2CYP3A4 | |
| SCHEMBL29353913 | 0.87 | MAPT (0.43) | POLBMAPTNPC1CYP1A2CYP3A4 | |
| SCHEMBL108341 | 0.87 | MAPT (0.43) | POLBMAPTNPC1CYP1A2CYP3A4 | |
| SCHEMBL28557156 | 0.86 | MAPT (0.42) | MAPTNPC1CYP1A2CYP3A4CYP2C9 | |
| SCHEMBL4542129 | 0.85 | MAPT (0.41) | POLBMAPTNPC1CYP1A2CYP3A4 | |
| SCHEMBL13066138 | 0.84 | MAPT (0.40) | POLBMAPTNPC1CYP1A2CYP3A4 | |
| SCHEMBL15392144 | 0.84 | MAPT (0.40) | POLBMAPTNPC1CYP1A2CYP3A4 | |
| SCHEMBL14556883 | 0.84 | MAPT (0.45) | POLBMAPTNPC1CYP1A2CYP3A4 | |
| SCHEMBL1615173 | 0.84 | CYP2C9 (0.41) | MAPTNPC1CYP1A2CYP3A4CYP2C9 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0520574-B1 | Thioxanthone derivatives | LAMBSON FINE CHEMICALS LIMITED (GB) | 2000-08-16 | — | — | EP | disclosed |
| US-5414092-A | Photoinitiators | INTERNATIONAL BIO-SYNTHETICS LIMITED (GB) | 1995-05-09 | — | — | US | disclosed |
| EP-0520574-A1 | Thioxanthone derivatives | GREAT LAKES FINE CHEMICALS LIMITED (GB) | 1992-12-30 | — | — | EP | disclosed |