1-Hydroxy-3-Ethoxybenzene

1-Hydroxy-3-Ethoxybenzene

SCHEMBL8065289

CCOc1cccc(O)c1.Nc1cccc(N)c1

nearest known ligand 0.73

Full drug profile on Sugi Atlas →

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
CYP3A4 P08684 3/20 0.73
TP53 P04637 1/20 0.73
TDP1 Q9NUW8 2/20 0.53
ALDH1A1 P00352 2/20 0.53
CA12 O43570 1/20 0.53
CA1 P00915 1/20 0.53
CA2 P00918 1/20 0.53
CA7 P43166 1/20 0.53
CA9 Q16790 1/20 0.53
CA14 Q9ULX7 1/20 0.53
TSHR P16473 2/20 0.50
CHRNB2 P17787 2/20 0.50
CHRNA4 P43681 2/20 0.50
MAOB P27338 1/20 0.49
APP P05067 2/20 0.46
CHRNB4 P30926 3/20 0.43
CHRNA3 P32297 3/20 0.43
NOTUM Q6P988 1/20 0.43
FYN P06241 1/20 0.43
NLRP3 Q96P20 1/20 0.43

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
1-Hydroxy-3-Ethoxybenzene SCHEMBL9773989 0.92 CYP3A4 (0.67) CYP3A4TP53TDP1ALDH1A1CA12
1-Hydroxy-3-Ethoxybenzene SCHEMBL365637 0.89 CHRNB2 (0.59) CYP3A4TP53ALDH1A1CHRNB2CHRNA4
1-Hydroxy-3-Ethoxybenzene SCHEMBL30597483 0.89 CHRNB2 (0.59) CYP3A4TP53ALDH1A1CHRNB2CHRNA4
1-Hydroxy-3-Ethoxybenzene SCHEMBL11135932 0.87 CHRNB2 (0.58) CYP3A4TP53ALDH1A1CA12CA2
SCHEMBL29371541 0.85 CYP3A4 (1.00) CYP3A4TP53TDP1ALDH1A1TSHR
SCHEMBL112380 0.85 CYP3A4 (1.00) CYP3A4TP53TDP1ALDH1A1TSHR
3-Aminophenol SCHEMBL9774329 0.84 CYP3A4 (0.56) CYP3A4TP53TDP1ALDH1A1CA12
Hydrochloric Acid SCHEMBL2871122 0.83 CYP3A4 (0.96) CYP3A4TP53TDP1ALDH1A1TSHR
1-Hydroxy-3-Ethoxybenzene SCHEMBL8073061 0.81 CHRNB2 (0.51) CYP3A4TP53TDP1ALDH1A1TSHR
1-Hydroxy-3-Propoxybenzene SCHEMBL7605942 0.81 CHRNB2 (0.60) CYP3A4TP53ALDH1A1TSHRCHRNB2

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-1007003-A1 CATIONIC AMPHIPHILE COMPOSITIONS FOR INTRACELLULAR DELIVERY OF THERAPEUTIC MOLECULES Genzyme Corporation (US) 2000-06-14 EP disclosed
EP-0954338-A2 CATIONIC AMPHIPHILE/DNA COMPLEXES Genzyme Corporation (US) 1999-11-10 EP disclosed
WO-1998013026-A1 CATIONIC AMPHIPHILE COMPOSITIONS FOR INTRACELLULAR DELIVERY OF THERAPEUTIC MOLECULES GENZYME CORPORATION (US) 1998-04-02 WO disclosed
WO-1998002190-A2 CATIONIC AMPHIPHILE/DNA COMPLEXES GENZYME CORPORATION (US) 1998-01-22 WO disclosed