SCHEMBL8065422

SCHEMBL8065422

CCN(CCCCO)c1ccc(N)cc1

nearest known ligand 0.62

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
ALDH1A1 P00352 5/20 0.62
TDP1 Q9NUW8 4/20 0.62
CYP3A4 P08684 3/20 0.62
MAPK1 P28482 2/20 0.62
PSMD14 O00487 2/20 0.62
L3MBTL1 Q9Y468 2/20 0.62
TSHR P16473 1/20 0.62
RECQL P46063 1/20 0.62
GFER P55789 1/20 0.62
ESRRG P62508 1/20 0.40
KDM4E B2RXH2 3/20 0.38
TP53 P04637 1/20 0.38
ALOX15 P16050 1/20 0.38
S100B P04271 1/20 0.37
ALDH3A1 P30838 1/20 0.36
ALDH1A3 P47895 1/20 0.36
MAPT P10636 4/20 0.36
NPC1 O15118 1/20 0.36
MITF O75030 1/20 0.36
RAB9A P51151 1/20 0.36

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL8063907 0.95 ALDH1A1 (0.64) ALDH1A1TDP1CYP3A4MAPK1PSMD14
SCHEMBL8622110 0.88 CYP3A4 (0.50) ALDH1A1TDP1CYP3A4MAPK1PSMD14
SCHEMBL33593 0.87 ALDH1A1 (0.69) ALDH1A1TDP1CYP3A4MAPK1PSMD14
SCHEMBL15202116 0.87 ALDH1A1 (0.47) ALDH1A1TDP1CYP3A4MAPK1PSMD14
SCHEMBL1274940 0.87 ALDH1A1 (0.42) ALDH1A1TDP1CYP3A4MAPK1PSMD14
Water SCHEMBL3892656 0.85 ALDH1A1 (0.67) ALDH1A1TDP1CYP3A4MAPK1PSMD14
SCHEMBL7039471 0.85 ALDH1A1 (0.67) ALDH1A1TDP1CYP3A4MAPK1PSMD14
Hydrochloric Acid SCHEMBL11224684 0.85 ALDH1A1 (0.67) ALDH1A1TDP1CYP3A4MAPK1PSMD14
Hydrochloric Acid SCHEMBL1154300 0.85 ALDH1A1 (0.67) ALDH1A1TDP1CYP3A4MAPK1PSMD14
SCHEMBL25189789 0.85 TDP1 (0.67) ALDH1A1TDP1CYP3A4MAPK1PSMD14

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-102482507-B Near-infrared absorbing film compositions IBM 2014-01-22 CN disclosed
CN-102482507-A Near-infrared absorbing film compositions IBM 2012-05-30 CN disclosed
EP-0654705-B1 Photographic processing composition and method of photographic processing using the same FUJI PHOTO FILM CO LTD (JP) 2000-06-21 EP disclosed
US-4233399-A Photographic elements containing amino-substituted hydroxy-pyridones CIBA-GEIGY AKTIENGESELLSCHAFT (CH) 1980-11-11 US disclosed