Predicted protein targets (top 14)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAPT | P10636 | 2/20 | 0.56 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.51 |
| ▸ | POLB | P06746 | 1/20 | 0.49 |
| ▸ | HSD17B2 | P37059 | 1/20 | 0.46 |
| ▸ | MAPK1 | P28482 | 2/20 | 0.43 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.43 |
| ▸ | MEN1 | O00255 | 1/20 | 0.43 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.43 |
| ▸ | CA1 | P00915 | 1/20 | 0.42 |
| ▸ | SLC6A2 | P23975 | 1/20 | 0.41 |
| ▸ | SLC6A4 | P31645 | 1/20 | 0.41 |
| ▸ | SLC6A3 | Q01959 | 1/20 | 0.41 |
| ▸ | HSD11B1 | P28845 | 1/20 | 0.41 |
| ▸ | AOC3 | Q16853 | 1/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8056693 | 1.00 | MAPT (0.56) | MAPTALDH1A1POLBHSD17B2MAPK1 | |
| SCHEMBL7483180 | 0.99 | MAPT (0.55) | MAPTALDH1A1POLBHSD17B2MAPK1 | |
| SCHEMBL7490400 | 0.99 | MAPT (0.55) | MAPTALDH1A1POLBHSD17B2MAPK1 | |
| SCHEMBL3485806 | 0.83 | ALDH1A1 (0.55) | MAPTALDH1A1HSD17B2MAPK1MEN1 | |
| SCHEMBL13254545 | 0.83 | ALDH1A1 (0.55) | MAPTALDH1A1HSD17B2MAPK1MEN1 | |
| SCHEMBL14292323 | 0.83 | ALDH1A1 (0.55) | MAPTALDH1A1HSD17B2MAPK1MEN1 | |
| SCHEMBL6676434 | 0.82 | ALDH1A1 (0.49) | ALDH1A1POLBMAPK1MEN1KMT2A | |
| SCHEMBL7961084 | 0.82 | MAPT (0.47) | MAPTALDH1A1POLBMAPK1MEN1 | |
| SCHEMBL7053572 | 0.78 | MAPT (0.61) | MAPTALDH1A1POLBL3MBTL1CA1 | |
| SCHEMBL4754009 | 0.78 | MAPT (0.61) | MAPTALDH1A1POLBL3MBTL1CA1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0736018-B1 | 4,5-DIARYLOXAZOLE DERIVATIVES | FUJISAWA PHARMACEUTICAL CO (JP) | 2000-07-05 | — | — | EP | disclosed |
| US-6025375-A | INHIBITORY ACTIVITY ON PLATELET AGGREGATION, VASODILATING ACTIVITY, ANTIHYPERTENSIVE ACTIVITY OR THE LIKE AND ARE PROSTAGLANDIN I.SUB.2 AGONISTS, | FUJISAWA PHARMACEUTICAL CO., LTD. (JP) | 2000-02-15 | — | — | US | disclosed |
| EP-0736018-A1 | 4,5-DIARYLOXAZOLE DERIVATIVES | FUJISAWA PHARMACEUTICAL CO., LTD. (JP) | 1996-10-09 | — | — | EP | disclosed |
| WO-1995017393-A1 | 4,5-DIARYLOXAZOLE DERIVATIVES | FUJISAWA PHARMACEUTICAL CO., LTD. (JP) | 1995-06-29 | — | — | WO | disclosed |