SCHEMBL80656

SCHEMBL80656

OCCCc1cccc2ccccc12

nearest known ligand 0.52

Predicted protein targets (top 18)

geneUniProtsupporting neighboursconfidence
MTNR1A P48039 2/20 0.50
CYP1A2 P05177 2/20 0.50
CYP2C19 P33261 2/20 0.50
CYP2C9 P11712 1/20 0.50
SIGMAR1 Q99720 1/20 0.50
TDP1 Q9NUW8 1/20 0.50
GPR84 Q9NQS5 1/20 0.49
KDM4E B2RXH2 1/20 0.49
ALDH1A1 P00352 1/20 0.49
GAA P10253 1/20 0.49
MAPT P10636 1/20 0.49
HPGD P15428 1/20 0.49
TSHR P16473 1/20 0.49
HSD17B10 Q99714 1/20 0.49
ACP3 P15309 1/20 0.48
MCL1 Q07820 2/20 0.48
CYP2D6 P10635 1/20 0.47
NQO2 P16083 1/20 0.46

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL31131331 1.00 MTNR1A (0.50) MTNR1ACYP1A2CYP2C19CYP2C9SIGMAR1
SCHEMBL132272 0.94 KDM4E (0.51) MTNR1ACYP1A2CYP2C19CYP2C9SIGMAR1
SCHEMBL128594 0.92 KDM4E (0.50) MTNR1ACYP1A2CYP2C19CYP2C9SIGMAR1
SCHEMBL129450 0.92 KDM4E (0.50) MTNR1ACYP1A2CYP2C19CYP2C9SIGMAR1
SCHEMBL3905548 0.92 KDM4E (0.50) MTNR1ACYP1A2CYP2C19CYP2C9SIGMAR1
SCHEMBL3262171 0.92 KDM4E (0.50) MTNR1ACYP1A2CYP2C19CYP2C9SIGMAR1
SCHEMBL12982187 0.92 KDM4E (0.50) MTNR1ACYP1A2CYP2C19CYP2C9SIGMAR1
SCHEMBL12981741 0.92 KDM4E (0.50) MTNR1ACYP1A2CYP2C19CYP2C9SIGMAR1
SCHEMBL6055152 0.89 HPRT1 (0.50) MTNR1ACYP1A2CYP2C19CYP2C9SIGMAR1
SCHEMBL27550 0.87 CYP1A2 (0.54) MTNR1ACYP1A2CYP2C19CYP2C9TDP1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 329 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-114436851-A Preparation method of N, N-dimethylbenzylamine and derivative thereof 常州大学 2022-05-06 CN claimed
CN-111233786-B Benzene sulfonamide compound containing five-membered heterocycle and preparation method and application thereof 中国人民解放军军事科学院军事医学研究院 2021-11-26 CN claimed
CN-111233786-A Benzene sulfonamide compound containing five-membered heterocycle and preparation method and application thereof 中国人民解放军军事科学院军事医学研究院 2020-06-05 CN claimed
EP-1673337-B1 Arylalkylcarbamate derivatives, preparation method thereof and use of same in therapeutics SANOFI SA (FR) 2011-11-23 EP claimed
EP-1590321-B1 ARYL ALKYL CARBAMATE DERIVATIVES PRODUCTION AND USE THEREOF IN THERAPY SANOFI AVENTIS (FR) 2010-04-28 EP claimed
US-7696374-B2 Arylalklcarbamate derivatives, preparation method thereof and use of same in therapeutics SANOFI-AVENTIS (FR) 2010-04-13 US claimed
US-7632850-B2 2-amino-2-oxoethyl 1-(4'-fluoro-1,1'-biphenyl-4-yl)cyclopropylmethylcarbamate and 2-(methylamino)-2-oxoethyl 1-(4'-fluoro-1,1'-biphenyl-4-yl)cyclopropylmethylcarbamate; fatty acid amide (FAAH) hyrdrolase inhibitors; analgesics; neuropathic pain;psychological disorders; anticarcinogenic agents; AIDS SANOFI-AVENTIS (FR) 2009-12-15 US claimed
US-20060223805-A1 Arylalklcarbamate derivatives, preparation method thereof and use of same in therapeutics SANOFI-AVENTIS (FR) 2006-10-05 US claimed
EP-1673337-A2 ARYLALKYLCARBAMATE DERIVATIVES, PREPARATION METHOD THEREOF AND USE OF SAME IN THERAPEUTICS Sanofi-Aventis (FR) 2006-06-28 EP claimed
US-20060014830-A1 Arylalkylcarbamate derivatives production and use thereof in therapy SANOFI-AVENTIS (FR) 2006-01-19 US claimed
EP-1590321-A2 ARYL ALKYL CARBAMATE DERIVATIVES PRODUCTION AND USE THEREOF IN THERAPY Sanofi-Aventis (FR) 2005-11-02 EP claimed
WO-2005033066-A2 ARYLALKYLCARBAMATE DERIVATIVES, PREPARATION METHOD THEREOF AND USE OF SAME IN THERAPEUTICS SANOFI-AVENTIS (FR) 2005-04-14 WO claimed
WO-2004067498-A2 ARYL ALKYL CARBAMATE DERIVATIVES PRODUCTION AND USE THEREOF IN THERAPY SANOFI-AVENTIS (FR) 2004-08-12 WO claimed
CN-1045391-C Oral delivery system BIOTECH AUSTRALIA PTY LTD (AU) 1999-10-06 CN claimed
CN-86107590-A Oral administration system 1987-05-20 CN claimed
US-4021421-A ENZYME INDUCING ACTIVITY RICHTER GEDEON VEGYESZETI GYAR RT. (HU) 1977-05-03 US claimed
EP-4728019-A1 A MICROWAVE CARBONIZATION ASSEMBLY AND METHOD FOR EXTRACTING COMPONENTS FROM RUBBER Sable Rubber IP Pty Limited (AU) 2026-04-22 EP disclosed
US-20250188376-A1 SUSTAINABLE AVIATION FUELS SARTEC CORPORATION 2025-06-12 US disclosed
EP-0498680-A1 New beta-amino-alpha-hydroxycarboxylic acids and their use Sankyo Company Limited (JP) 1992-08-12 EP disclosed
US-4045433-A SEDATIVES RICHTER GEDEON VEGYESZETI GYAR RT. (HU) 1977-08-30 US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20060014830-A1 Arylalkylcarbamate derivatives production and use thereof in therapy CBR3, H4C1; H4C2; H4C3; H4C4; H4C5; H4C6; H4C8; H4C9; H4C11; H4C12; H4C13; H4C14; H4C15; H4C16, C5 MTNR1A 2092/4885CYP1A2 469/4885CYP2C19 543/4885
US-20060223805-A1 Arylalklcarbamate derivatives, preparation method thereof and use of same in therapeutics GBA1, NAT1, AADAC MTNR1A 1655/4885CYP1A2 848/4885CYP2C19 1169/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.