Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | LMNA | P02545 | 2/20 | 0.64 |
| ▸ | MEN1 | O00255 | 4/20 | 0.52 |
| ▸ | KMT2A | Q03164 | 4/20 | 0.52 |
| ▸ | GSK3B | P49841 | 2/20 | 0.52 |
| ▸ | ALDH1A1 | P00352 | 6/20 | 0.50 |
| ▸ | HSD17B10 | Q99714 | 5/20 | 0.50 |
| ▸ | KDM4E | B2RXH2 | 4/20 | 0.50 |
| ▸ | MAPT | P10636 | 3/20 | 0.50 |
| ▸ | HPGD | P15428 | 2/20 | 0.50 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.48 |
| ▸ | TSHR | P16473 | 3/20 | 0.47 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.47 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.47 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.47 |
| ▸ | MAPK1 | P28482 | 2/20 | 0.46 |
| ▸ | PPARG | P37231 | 1/20 | 0.45 |
| ▸ | NCOA2 | Q15596 | 1/20 | 0.45 |
| ▸ | NCOA1 | Q15788 | 1/20 | 0.45 |
| ▸ | NCOA3 | Q9Y6Q9 | 1/20 | 0.45 |
| ▸ | TP53 | P04637 | 1/20 | 0.44 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8059444 | 0.88 | GSK3B (0.54) | LMNAMEN1KMT2AGSK3BALDH1A1 | |
| SCHEMBL8065137 | 0.87 | GSK3B (0.53) | LMNAMEN1KMT2AGSK3BALDH1A1 | |
| Lithium Ion SCHEMBL8065141 | 0.86 | GSK3B (0.53) | LMNAMEN1KMT2AGSK3BALDH1A1 | |
| SCHEMBL8065368 | 0.82 | GSK3B (0.58) | LMNAMEN1KMT2AGSK3BKDM4E | |
| SCHEMBL8047974 | 0.78 | SMN1; SMN2 (0.51) | LMNAMEN1KMT2AALDH1A1HSD17B10 | |
| SCHEMBL27541239 | 0.73 | GSK3B (0.66) | LMNAGSK3BALDH1A1KDM4EGAA | |
| SCHEMBL472899 | 0.72 | GSK3B (0.55) | MEN1KMT2AGSK3BKDM4EMAPT | |
| SCHEMBL1167311 | 0.71 | GSK3B (0.60) | MEN1KMT2AGSK3BKDM4EGAA | |
| SCHEMBL6372051 | 0.70 | ADORA2A (0.60) | LMNAMEN1KMT2AGSK3BALDH1A1 | |
| SCHEMBL8059585 | 0.70 | GSK3B (0.58) | GSK3BKDM4EGAA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-6096770-A | ADMINISTERING ORALLY OR PARENTALLY, TO A PATIENT AN ANTHRANILIC ACID DERIVATIVE FOR REDUCING THE ADVERSE EFFECTS OF SMOOTH MUSCLE CONTRACTIONS | AMERICAN HOME PRODUCTS CORPORATION (US) | 2000-08-01 | — | — | US | disclosed |
| EP-1003713-A1 | ANTHRANILIC ACID ANALOGS | AMERICAN HOME PRODUCTS CORPORATION (US) | 2000-05-31 | — | — | EP | disclosed |
| WO-1999007670-A1 | ANTHRANILIC ACID ANALOGS | AMERICAN HOME PRODUCTS CORPORATION (US) | 1999-02-18 | — | — | WO | disclosed |