Predicted protein targets (top 14)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | GSK3B | P49841 | 9/20 | 0.58 |
| ▸ | CDK2 | P24941 | 4/20 | 0.46 |
| ▸ | TRPV1 | Q8NER1 | 1/20 | 0.45 |
| ▸ | GAA | P10253 | 1/20 | 0.44 |
| ▸ | FBP1 | P09467 | 1/20 | 0.43 |
| ▸ | ADORA2A | P29274 | 1/20 | 0.42 |
| ▸ | HCRTR2 | O43614 | 1/20 | 0.42 |
| ▸ | IDO1 | P14902 | 1/20 | 0.41 |
| ▸ | CFTR | P13569 | 1/20 | 0.40 |
| ▸ | LMNA | P02545 | 1/20 | 0.40 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.40 |
| ▸ | MEN1 | O00255 | 2/20 | 0.40 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.40 |
| ▸ | NPC1 | O15118 | 1/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL472899 | 0.85 | GSK3B (0.55) | GSK3BCDK2GAAFBP1IDO1 | |
| SCHEMBL27905112 | 0.84 | KDM4E (0.47) | GSK3BCDK2GAAFBP1ADORA2A | |
| SCHEMBL14564447 | 0.82 | MEN1 (0.55) | GSK3BCDK2GAAFBP1ADORA2A | |
| SCHEMBL9722654 | 0.82 | GSK3B (0.55) | GSK3BCDK2GAAFBP1ADORA2A | |
| SCHEMBL1167311 | 0.82 | GSK3B (0.60) | GSK3BTRPV1GAAFBP1ADORA2A | |
| SCHEMBL8065609 | 0.82 | LMNA (0.64) | GSK3BGAALMNAKDM4EMEN1 | |
| SCHEMBL6372051 | 0.81 | ADORA2A (0.60) | GSK3BCDK2GAAFBP1ADORA2A | |
| SCHEMBL8059585 | 0.81 | GSK3B (0.58) | GSK3BTRPV1GAAADORA2AKDM4E | |
| SCHEMBL1931754 | 0.81 | GAA (0.65) | GSK3BCDK2GAAFBP1ADORA2A | |
| SCHEMBL1969272 | 0.81 | ADORA2A (0.64) | GSK3BCDK2GAAFBP1ADORA2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-1265643-A | Anthranilic acid analogs | AMERICAN HOME PROD (US) | 2000-09-06 | — | — | CN | disclosed |
| US-6096770-A | ADMINISTERING ORALLY OR PARENTALLY, TO A PATIENT AN ANTHRANILIC ACID DERIVATIVE FOR REDUCING THE ADVERSE EFFECTS OF SMOOTH MUSCLE CONTRACTIONS | AMERICAN HOME PRODUCTS CORPORATION (US) | 2000-08-01 | — | — | US | disclosed |
| EP-1003713-A1 | ANTHRANILIC ACID ANALOGS | AMERICAN HOME PRODUCTS CORPORATION (US) | 2000-05-31 | — | — | EP | disclosed |
| WO-1999007670-A1 | ANTHRANILIC ACID ANALOGS | AMERICAN HOME PRODUCTS CORPORATION (US) | 1999-02-18 | — | — | WO | disclosed |