Predicted protein targets (top 3)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | FOLH1 | Q04609 | 1/20 | 0.41 |
| ▸ | GGH | Q92820 | 1/20 | 0.39 |
| ▸ | NAALAD2 | Q9Y3Q0 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL5052846 | 0.84 | GGH (0.43) | FOLH1GGHNAALAD2 | |
| SCHEMBL7604513 | 0.83 | GGH (0.42) | FOLH1GGHNAALAD2 | |
| SCHEMBL5051128 | 0.79 | GGH (0.39) | FOLH1GGHNAALAD2 | |
| SCHEMBL5052989 | 0.76 | FOLH1 (0.46) | FOLH1NAALAD2 | |
| SCHEMBL5060148 | 0.75 | FOLH1 (0.42) | FOLH1GGHNAALAD2 | |
| SCHEMBL5053024 | 0.75 | FOLH1 (0.57) | FOLH1NAALAD2 | |
| SCHEMBL7607505 | 0.75 | GGH (0.51) | FOLH1GGH | |
| SCHEMBL15456541 | 0.75 | ACP3 (0.50) | — | |
| SCHEMBL28289198 | 0.75 | CPA3 (0.42) | FOLH1NAALAD2 | |
| SCHEMBL5054388 | 0.74 | GGH (0.58) | FOLH1GGHNAALAD2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1005348-A1 | NAALADASE COMPOSITIONS AND METHODS FOR TREATING GLUTAMATE ABNORMALITY AND EFFECTING NEURONAL ACTIVITY IN ANIMALS | GUILFORD PHARMACEUTICALS INC. (US) | 2000-06-07 | — | — | EP | disclosed |
| WO-1998013046-A1 | NAALADASE COMPOSITIONS AND METHODS FOR TREATING GLUTAMATE ABNORMALITY AND EFFECTING NEURONAL ACTIVITY IN ANIMALS | GUILFORD PHARMACEUTICALS INC. (US) | 1998-04-02 | — | — | WO | disclosed |