SCHEMBL8065624

SCHEMBL8065624

COc1cccc(-c2cc(CCNC(=O)CS)c3cc(OC)ccc3c2)c1

nearest known ligand 0.70

Predicted protein targets (top 2)

geneUniProtsupporting neighboursconfidence
MTNR1A P48039 19/20 0.70
MTNR1B P49286 18/20 0.70

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL6247009 0.89 MTNR1A (0.85) MTNR1AMTNR1B
SCHEMBL8064745 0.87 MTNR1A (0.72) MTNR1AMTNR1B
SCHEMBL8065619 0.84 MTNR1A (0.67) MTNR1AMTNR1B
SCHEMBL6246695 0.83 MTNR1A (0.80) MTNR1AMTNR1B
SCHEMBL6245575 0.83 MTNR1A (0.78) MTNR1AMTNR1B
SCHEMBL5929461 0.83 MTNR1A (0.82) MTNR1AMTNR1B
SCHEMBL5929478 0.83 MTNR1A (1.00) MTNR1AMTNR1B
SCHEMBL6142835 0.83 MTNR1A (0.82) MTNR1AMTNR1B
SCHEMBL5929501 0.82 MTNR1A (0.80) MTNR1AMTNR1B
SCHEMBL5929489 0.82 MTNR1A (1.00) MTNR1AMTNR1B

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-6143789-A ENANTIOMORPHS ADIR ET COMPAGNIE (FR) 2000-11-07 US disclosed