Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | POLB | P06746 | 2/20 | 0.49 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.49 |
| ▸ | ADRA2A | P08913 | 1/20 | 0.46 |
| ▸ | ADRA2B | P18089 | 1/20 | 0.46 |
| ▸ | ADRA2C | P18825 | 1/20 | 0.46 |
| ▸ | PTGDR2 | Q9Y5Y4 | 1/20 | 0.46 |
| ▸ | CES1 | P23141 | 2/20 | 0.45 |
| ▸ | CES2 | O00748 | 1/20 | 0.45 |
| ▸ | HTR7 | P34969 | 1/20 | 0.43 |
| ▸ | MAPT | P10636 | 4/20 | 0.43 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.43 |
| ▸ | MEN1 | O00255 | 2/20 | 0.43 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.43 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.42 |
| ▸ | LMNA | P02545 | 1/20 | 0.42 |
| ▸ | RECQL | P46063 | 1/20 | 0.42 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.42 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.42 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.42 |
| ▸ | IKBKB | O14920 | 1/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8065631 | 0.89 | POLB (0.51) | POLBMAPK1ADRA2AADRA2BADRA2C | |
| SCHEMBL8065636 | 0.89 | POLB (0.51) | POLBMAPK1ADRA2AADRA2BADRA2C | |
| SCHEMBL25285573 | 0.88 | ADRA2A (0.47) | POLBMAPK1ADRA2AADRA2BADRA2C | |
| SCHEMBL17796922 | 0.88 | POLB (0.46) | POLBMAPK1ADRA2AADRA2BADRA2C | |
| SCHEMBL27737793 | 0.84 | POLB (0.43) | POLBMAPK1ADRA2AADRA2BADRA2C | |
| SCHEMBL8063661 | 0.83 | AKR1C3 (0.51) | ADRA2AADRA2BADRA2CPTGDR2CES1 | |
| SCHEMBL9812692 | 0.83 | ADRA2A (0.50) | POLBMAPK1ADRA2AADRA2BADRA2C | |
| Water SCHEMBL11780560 | 0.81 | ADRA2A (0.49) | POLBMAPK1ADRA2AADRA2BADRA2C | |
| SCHEMBL9978745 | 0.81 | CYP1B1 (0.50) | MAPK1MAPTKMT2AMEN1KDM4E | |
| SCHEMBL9978744 | 0.81 | CYP1B1 (0.50) | MAPK1MAPTKMT2AMEN1KDM4E |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-6143917-A | FROM A DIARYL CARBONATE AND AN AMINE COMPOUND HAVING AT LEAST ONE HYDROGEN ATOM LOCATED AT AN N-POSITION UNDER MODERATE CONDITIONS AT A HIGH REACTION RATE WITH A HIGH SELECTIVITY AND WITH A HIGH YIELD | UBE INDUSTRIES, LTD. (JP) | 2000-11-07 | — | — | US | disclosed |
| EP-0902014-A1 | PROCESS FOR PRODUCING ARYL CARBAMATES | UBE INDUSTRIES LIMITED (JP) | 1999-03-17 | — | — | EP | disclosed |