Predicted protein targets (top 3)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MMP13 | P45452 | 20/20 | 0.87 |
| ▸ | MMP3 | P08254 | 1/20 | 0.65 |
| ▸ | SLC22A8 | Q8TCC7 | 1/20 | 0.64 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8072171 | 0.95 | MMP13 (0.80) | MMP13MMP3SLC22A8 | |
| SCHEMBL8073489 | 0.93 | MMP13 (1.00) | MMP13MMP3SLC22A8 | |
| SCHEMBL8066195 | 0.92 | MMP13 (0.88) | MMP13MMP3SLC22A8 | |
| SCHEMBL3687710 | 0.91 | MMP13 (0.78) | MMP13MMP3SLC22A8 | |
| SCHEMBL3687700 | 0.91 | MMP13 (0.78) | MMP13MMP3SLC22A8 | |
| SCHEMBL8070875 | 0.91 | MMP13 (0.78) | MMP13MMP3SLC22A8 | |
| SCHEMBL3688002 | 0.91 | MMP13 (0.87) | MMP13MMP3SLC22A8 | |
| SCHEMBL8065070 | 0.91 | MMP13 (0.87) | MMP13MMP3SLC22A8 | |
| SCHEMBL8065041 | 0.91 | MMP13 (0.87) | MMP13MMP3SLC22A8 | |
| SCHEMBL8070859 | 0.91 | MMP13 (0.87) | MMP13MMP3SLC22A8 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-101815710-A | Pyrimidine and pyridine derivatives, their pharmaceutical use and compositions | PFIZER | 2010-08-25 | — | — | CN | disclosed |
| WO-2009016498-A1 | PYRIMIDINE AND PYRIDINE DERIVATIVES AND THEIR PHARMACEUTICAL USE AND COMPOSITIONS | PFIZER INC. (US) | 2009-02-05 | — | — | WO | disclosed |