SCHEMBL8065727

SCHEMBL8065727

CCCCCCCCSC(C)Sc1nc(Oc2cc(C(C)(C)C)c(O)c(C(C)(C)C)c2)nc(Oc2cc(C(C)(C)C)c(O)c(C(C)(C)C)c2)n1

nearest known ligand 0.35

Predicted protein targets (top 14)

geneUniProtsupporting neighboursconfidence
▸ CA1 P00915 1/20 0.35
▸ CA2 P00918 1/20 0.35
▸ PTGS1 P23219 4/20 0.33
▸ PTGS2 P35354 1/20 0.33
▸ HPN P05981 1/20 0.32
▸ MAPT P10636 1/20 0.32
▸ ALOX15 P16050 1/20 0.32
▸ SIRT5 Q9NXA8 1/20 0.32
▸ GAA P10253 1/20 0.31
▸ XBP1 P17861 1/20 0.31
▸ ATM Q13315 1/20 0.31
▸ NPSR1 Q6W5P4 1/20 0.31
▸ L3MBTL1 Q9Y468 1/20 0.31
▸ VCAM1 P19320 1/20 0.30

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL11173084 1.00 CA1 (0.35) CA1CA2PTGS1PTGS2HPN
SCHEMBL11182460 0.98 CA1 (0.35) CA1CA2PTGS1PTGS2HPN
SCHEMBL11172096 0.98 CA1 (0.35) CA1CA2PTGS1PTGS2HPN
SCHEMBL11713619 0.90 CA1 (0.33) CA1CA2PTGS1PTGS2HPN
SCHEMBL11169680 0.88 CA1 (0.34) CA1CA2PTGS1PTGS2HPN
SCHEMBL11173246 0.86 GAA (0.43) MAPTALOX15GAAXBP1ATM
SCHEMBL11174038 0.86 CA1 (0.34) CA1CA2PTGS1PTGS2HPN
SCHEMBL4215012 0.84 CA2 (0.36) CA1CA2PTGS1PTGS2HPN
SCHEMBL39436 0.83 CA1 (0.40) CA1CA2PTGS1PTGS2HPN
SCHEMBL11863295 0.83 CA1 (0.40) CA1CA2PTGS1PTGS2HPN

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 53 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-0902853-B1 THERMALLY STABLE ACOUSTICAL INSULATION MINNESOTA MINING & MFG (US) 2000-05-24 — — EP disclosed
US-5961904-A Method of making a thermally stable acoustical insulation microfiber web MINNESOTA MINING AND MANUFACTURING CO. (US) 1999-10-05 — — US disclosed
US-5773375-A MELT BLOWN POLYPROPYLENE WEB, FOR AUTOMOBILES MINNESOTA MINING AND MANUFACTURING COMPANY 1998-06-30 — — US disclosed
US-RE31343-E STABILIZERS FOR POLYMERS CIBA-GEIGY CORPORATION (US) 1983-08-09 — — US disclosed
US-RE31342-E STABILIZERS FOR POLYMERS CIBA-GEIGY CORPORATION (US) 1983-08-09 — — US disclosed
US-4238575-A POLYALKYLTHIOETHYL METHACRYLATE, POLYOLEFINS CIBA-GEIGY CORPORATION (US) 1980-12-09 — — US disclosed
US-4233208-A OXIDATION RESISTANCE, RADIATION RESISTANCE CIBA-GEIGY CORPORATION (US) 1980-11-11 — — US disclosed
US-4219464-A Hindered piperidine carboxylic acids, metal salts thereof and stabilized compositions CIBA-GEIGY CORPORATION (US) 1980-08-26 — — US disclosed
US-4208522-A POLYMER STABILIZERS CIBA-GEIGY CORPORATION (US) 1980-06-17 — — US disclosed
US-4207229-A STABILIZING POLYPROPYLENE AGAINST THERNAL, OXIDATIVE AND ULTRAVIOLET LIGHT DEGRADATION CIBA-GEIGY CORPORATION (US) 1980-06-10 — — US disclosed
US-3991012-A AGAINST ULTRAVIOLET DETERIORATION OF POLYMERS CIBA-GEIGY CORPORATION (US) 1976-11-09 — — US disclosed
US-3979360-A Compositions stabilized with benzoyloxybenzamides CIBA-GEIGY CORPORATION (US) 1976-09-07 — — US disclosed
US-3969316-A 3,5-Dialkyl-4-hydroxyphenylalkyl substituted piperazine diones and polymeric compositions stabilized thereby CIBA-GEIGY CORPORATION (US) 1976-07-13 — — US disclosed
US-3968078-A Alkyl alkanoate derivatives of substituted piperazine-diones and polymer compositions stabilized thereby CIBA-GEIGY CORPORATION (US) 1976-07-06 — — US disclosed
US-3960809-A POLYMERS CIBA-GEIGY CORPORATION (US) 1976-06-01 — — US disclosed
US-3943102-A Compositions stabilized with polyol esters of benzoyloxybenzoic acids CIBA-GEIGY CORPORATION (US) 1976-03-09 — — US disclosed
US-3941746-A Containing hindered phenolic norbornane-2,3-dicarboximides stabilized compositions CIBA-GEIGY CORPORATION (US) 1976-03-02 — — US disclosed
US-3939163-A Metal salts of hindered piperidine carboxylic acids and stabilized compositions CIBA-GEIGY CORPORATION (US) 1976-02-17 — — US disclosed
US-3937711-A POLYMERIC STABILIZERS, POLYOLEFINS CIBA-GEIGY CORPORATION (US) 1976-02-10 — — US disclosed
US-3936456-A Substituted piperazine dione oxyls and hydroxides and polymer compositions stabilized thereby CIBY-GEIGY CORPORATION (US) 1976-02-03 — — US disclosed
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