Predicted protein targets (top 3)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | USP30 | Q70CQ3 | 1/20 | 0.54 |
| ▸ | EPHX1 | P07099 | 18/20 | 0.53 |
| ▸ | EPHX2 | P34913 | 18/20 | 0.53 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4542472 | 1.00 | USP30 (0.54) | USP30EPHX1EPHX2 | |
| SCHEMBL4537166 | 0.95 | USP30 (0.50) | USP30EPHX1EPHX2 | |
| SCHEMBL4543056 | 0.94 | EPHX1 (0.57) | USP30EPHX1EPHX2 | |
| SCHEMBL4541039 | 0.89 | EPHX1 (0.60) | EPHX1EPHX2 | |
| SCHEMBL4537470 | 0.87 | TAS1R3 (0.46) | USP30EPHX1EPHX2 | |
| SCHEMBL4542310 | 0.86 | EPHX2 (0.57) | EPHX1EPHX2 | |
| SCHEMBL8069489 | 0.83 | EPHX1 (0.49) | EPHX1EPHX2 | |
| SCHEMBL4530345 | 0.83 | EPHX1 (0.49) | EPHX1EPHX2 | |
| SCHEMBL4535609 | 0.83 | EPHX1 (0.65) | EPHX1EPHX2 | |
| SCHEMBL8064706 | 0.82 | EPHX2 (0.61) | EPHX1EPHX2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2009070497-A1 | SEH AND 11 β-HSD1 INHIBITORS AND THEIR USE | SMITHKLINE BEECHAM CORPORATION (US) | 2009-06-04 | — | — | WO | disclosed |