Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | NR4A2 | P43354 | 3/20 | 0.58 |
| ▸ | SOS2 | Q07890 | 1/20 | 0.58 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.56 |
| ▸ | CCR1 | P32246 | 1/20 | 0.53 |
| ▸ | MAPT | P10636 | 3/20 | 0.53 |
| ▸ | GAA | P10253 | 2/20 | 0.53 |
| ▸ | ATM | Q13315 | 1/20 | 0.53 |
| ▸ | PRNP | P04156 | 2/20 | 0.51 |
| ▸ | RXFP1 | Q9HBX9 | 2/20 | 0.51 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.51 |
| ▸ | FERMT2 | Q96AC1 | 2/20 | 0.50 |
| ▸ | TDP1 | Q9NUW8 | 2/20 | 0.49 |
| ▸ | PKM | P14618 | 2/20 | 0.49 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.49 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.49 |
| ▸ | CASP1 | P29466 | 1/20 | 0.49 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.49 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.48 |
| ▸ | CHKA | P35790 | 1/20 | 0.47 |
| ▸ | POLB | P06746 | 1/20 | 0.47 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8125793 | 0.82 | NR4A2 (0.50) | NR4A2SOS2CYP1A2CCR1MAPT | |
| SCHEMBL8367161 | 0.81 | NR4A2 (0.58) | NR4A2SOS2CYP1A2CCR1MAPT | |
| SCHEMBL1496353 | 0.81 | KDM4E (0.43) | NR4A2SOS2CYP1A2CCR1MAPT | |
| SCHEMBL4748775 | 0.81 | POLB (0.62) | CYP1A2CCR1MAPTGAAATM | |
| SCHEMBL8128028 | 0.80 | NR4A2 (0.49) | NR4A2SOS2CYP1A2CCR1MAPT | |
| SCHEMBL6388963 | 0.79 | CYP1A2 (0.54) | NR4A2SOS2CYP1A2CCR1MAPT | |
| SCHEMBL11472817 | 0.79 | CYP3A4 (0.44) | NR4A2SOS2CYP1A2CCR1MAPT | |
| SCHEMBL24338855 | 0.78 | FERMT2 (0.50) | MAPTGAAKDM4EFERMT2 | |
| SCHEMBL1496398 | 0.78 | ALK (0.51) | CYP1A2MAPTKDM4E | |
| SCHEMBL30174534 | 0.78 | FERMT2 (0.50) | MAPTGAAKDM4EFERMT2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 9 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-115515956-B | Benzimidazole derivative, and preparation method and medical application thereof | 深圳信立泰药业股份有限公司 | 2024-06-25 | — | — | CN | disclosed |
| CN-115515956-A | Benzimidazole derivative and preparation method and medical application thereof | 深圳信立泰药业股份有限公司 | 2022-12-23 | — | — | CN | disclosed |
| WO-2022068772-A1 | BENZIMIDAZOLE DERIVATIVE, AND PREPARATION METHOD THEREFOR, AND MEDICAL USE THEREOF | 深圳信立泰药业股份有限公司 | 2022-04-07 | — | — | WO | disclosed |
| WO-2022068772-A1 | BENZIMIDAZOLE DERIVATIVE, AND PREPARATION METHOD THEREFOR, AND MEDICAL USE THEREOF | 深圳信立泰药业股份有限公司 | 2022-04-07 | — | — | WO | disclosed |
| US-6117884-A | 4-substituted quinoline derivatives having fungicidal activity | DAEUBLE JOHN (US) | 2000-09-12 | — | — | US | disclosed |
| CN-1228084-A | 4-substituted quinoline derivatives having fungicidal activity | DOW AGROSCIENCES LLC (US) | 1999-09-08 | — | — | CN | disclosed |
| EP-0925282-A1 | 4-SUBSTITUTED QUINOLINE DERIVATIVES HAVING FUNGICIDAL ACTIVITY | DOWELANCO (US) | 1999-06-30 | — | — | EP | disclosed |
| WO-1998005645-A9 | 4-SUBSTITUTED QUINOLINE DERIVATIVES HAVING FUNGICIDAL ACTIVITY | — | 1998-08-20 | — | — | WO | disclosed |
| WO-1998005645-A1 | 4-SUBSTITUTED QUINOLINE DERIVATIVES HAVING FUNGICIDAL ACTIVITY | DOW AGROSCIENCES LLC (US) | 1998-02-12 | — | — | WO | disclosed |