Predicted protein targets (top 18)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | POLB | P06746 | 3/20 | 0.46 |
| ▸ | MAPT | P10636 | 3/20 | 0.46 |
| ▸ | HSD17B10 | Q99714 | 5/20 | 0.44 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.44 |
| ▸ | HPGD | P15428 | 4/20 | 0.44 |
| ▸ | KDM4E | B2RXH2 | 3/20 | 0.44 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.43 |
| ▸ | RECQL | P46063 | 1/20 | 0.43 |
| ▸ | MEN1 | O00255 | 5/20 | 0.43 |
| ▸ | KMT2A | Q03164 | 5/20 | 0.43 |
| ▸ | SLC5A1 | P13866 | 1/20 | 0.43 |
| ▸ | SLC5A2 | P31639 | 1/20 | 0.43 |
| ▸ | RXFP1 | Q9HBX9 | 1/20 | 0.42 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.42 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.42 |
| ▸ | CYP19A1 | P11511 | 3/20 | 0.41 |
| ▸ | AKR1C3 | P42330 | 2/20 | 0.39 |
| ▸ | TSHR | P16473 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8057631 | 1.00 | POLB (0.46) | POLBMAPTHSD17B10ALDH1A1HPGD | |
| SCHEMBL8057862 | 0.93 | HSD17B10 (0.44) | POLBMAPTHSD17B10ALDH1A1HPGD | |
| SCHEMBL8071978 | 0.93 | HSD17B10 (0.44) | POLBMAPTHSD17B10ALDH1A1HPGD | |
| SCHEMBL8057540 | 0.92 | HSD17B10 (0.44) | POLBMAPTHSD17B10ALDH1A1HPGD | |
| SCHEMBL5508781 | 0.88 | SLC5A1 (0.41) | POLBMAPTHSD17B10ALDH1A1HPGD | |
| SCHEMBL8073571 | 0.88 | SLC5A1 (0.41) | POLBMAPTHSD17B10ALDH1A1HPGD | |
| SCHEMBL8071738 | 0.86 | ALDH1A1 (0.41) | POLBMAPTHSD17B10ALDH1A1HPGD | |
| SCHEMBL7831300 | 0.83 | SMN1; SMN2 (0.48) | POLBMAPTHSD17B10ALDH1A1HPGD | |
| SCHEMBL8066745 | 0.83 | POLB (0.44) | POLBMAPTHSD17B10ALDH1A1HPGD | |
| SCHEMBL8066864 | 0.83 | POLB (0.49) | POLBMAPTHSD17B10ALDH1A1HPGD |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-6093714-A | AN ANTIALLERGENS FOR TREATMENT AND PREVENTION OF BRONCHIAL ASTHMA, ECZEMA, HIVES, ALLERGIC GASTROINTESTINAL TROUBLES, ALLERGIC RHINITIS, ALLERGIC CONJUNCTIVITIS | MEIJI SEIKA KAISHA, LTD. (JP) | 2000-07-25 | — | — | US | disclosed |
| EP-0834512-A1 | TRICYCLIC BENZAZEPINE COMPOUNDS | MEIJI SEIKA KAISHA LTD. (JP) | 1998-04-08 | — | — | EP | disclosed |