Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CES1 | P23141 | 6/20 | 0.50 |
| ▸ | SRC | P12931 | 1/20 | 0.46 |
| ▸ | MEN1 | O00255 | 1/20 | 0.44 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.44 |
| ▸ | CES2 | O00748 | 4/20 | 0.42 |
| ▸ | TSHR | P16473 | 4/20 | 0.42 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.42 |
| ▸ | DAO | P14920 | 1/20 | 0.42 |
| ▸ | NAPRT | Q6XQN6 | 1/20 | 0.42 |
| ▸ | PTPN1 | P18031 | 1/20 | 0.40 |
| ▸ | GSK3B | P49841 | 1/20 | 0.40 |
| ▸ | AKR1C3 | P42330 | 1/20 | 0.40 |
| ▸ | AKR1C2 | P52895 | 1/20 | 0.40 |
| ▸ | AKR1C1 | Q04828 | 1/20 | 0.40 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.39 |
| ▸ | HIF1A | Q16665 | 1/20 | 0.39 |
| ▸ | HPGD | P15428 | 1/20 | 0.39 |
| ▸ | HSD17B10 | Q99714 | 2/20 | 0.39 |
| ▸ | TDP1 | Q9NUW8 | 2/20 | 0.39 |
| ▸ | POLB | P06746 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8821889 | 0.78 | CES1 (0.50) | CES1SRCMEN1KMT2ACES2 | |
| SCHEMBL2322081 | 0.77 | CES1 (0.59) | CES1SRCMEN1KMT2ACES2 | |
| SCHEMBL1799477 | 0.76 | CES1 (0.64) | CES1SRCMEN1KMT2ACES2 | |
| SCHEMBL758154 | 0.75 | CES1 (0.56) | CES1SRCCES2TSHRALDH1A1 | |
| SCHEMBL25930136 | 0.75 | CES1 (0.56) | CES1SRCMEN1KMT2ACES2 | |
| SCHEMBL7528244 | 0.74 | CES1 (0.61) | CES1SRCMEN1KMT2ACES2 | |
| SCHEMBL11437544 | 0.74 | CES1 (0.45) | CES1SRCMEN1KMT2ACES2 | |
| SCHEMBL6427462 | 0.74 | CES1 (0.50) | CES1SRCMEN1KMT2ACES2 | |
| Hydrogen Sulfide SCHEMBL28239188 | 0.73 | CES1 (0.54) | CES1SRCCES2TSHRALDH1A1 | |
| SCHEMBL31323287 | 0.72 | CES1 (0.58) | CES1SRCMEN1KMT2ACES2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0798294-B1 | Process for preparing alpha-haloacetophenone derivative | SUMITOMO SEIKA CHEMICALS (JP) | 2000-06-14 | — | — | EP | disclosed |
| US-5821388-A | Process for preparing α-haloacetophenone derivative | SUMITOMO SEIKA CHEMICAL CO., LTD. (JP) | 1998-10-13 | — | — | US | disclosed |
| EP-0798294-A2 | Process for preparing haloacetophenone derivative | SUMITOMO SEIKA CHEMICALS CO., LTD. (JP) | 1997-10-01 | — | — | EP | disclosed |