SCHEMBL758154

SCHEMBL758154

CC(C)(Br)C(=O)c1ccccc1

nearest known ligand 0.56

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
CES1 P23141 6/20 0.56
SRC P12931 1/20 0.50
TSHR P16473 4/20 0.48
CES2 O00748 4/20 0.48
ALDH1A1 P00352 2/20 0.48
DAO P14920 1/20 0.48
NAPRT Q6XQN6 1/20 0.48
HSD17B10 Q99714 2/20 0.47
TDP1 Q9NUW8 2/20 0.47
PTPN1 P18031 1/20 0.44
GSK3B P49841 1/20 0.44
POLB P06746 2/20 0.44
CYP3A4 P08684 1/20 0.44
PARP1 P09874 1/20 0.44
MAPT P10636 1/20 0.44
CYP2C19 P33261 1/20 0.44
RECQL P46063 1/20 0.44
BLM P54132 1/20 0.44
PMP22 Q01453 1/20 0.44
L3MBTL1 Q9Y468 1/20 0.44

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
Hydrogen Sulfide SCHEMBL28239188 0.98 CES1 (0.54) CES1SRCTSHRCES2ALDH1A1
SCHEMBL11850419 0.89 CES1 (0.47) CES1SRCTSHRCES2ALDH1A1
SCHEMBL25930136 0.85 CES1 (0.56) CES1SRCTSHRCES2ALDH1A1
SCHEMBL1445897 0.83 CES1 (0.54) CES1SRCTSHRCES2ALDH1A1
SCHEMBL4618681 0.82 CES1 (0.58) CES1SRCTSHRCES2ALDH1A1
SCHEMBL21109870 0.82 CES1 (0.58) CES1SRCTSHRCES2ALDH1A1
SCHEMBL226691 0.82 CES1 (0.58) CES1SRCTSHRCES2ALDH1A1
SCHEMBL1553905 0.82 PARP10 (0.56) ALDH1A1POLBMAPTL3MBTL1
SCHEMBL1553692 0.82 HPGD (0.61) CES1ALDH1A1TDP1POLBMAPT
SCHEMBL1799477 0.81 CES1 (0.64) CES1SRCTSHRCES2ALDH1A1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 241 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-1721992-B Star polymer SUMITOMO CHEMICAL CO 2011-02-02 CN claimed
US-20060258867-A1 Transition metal complexes, especially iron complexes, used as a catalyst component in the polymerisation of olefins IC INNOVATIONS LTD. (GB) 2006-11-16 US claimed
CN-1721992-A Star polymer SUMITOMO CHEMICAL CO 2006-01-18 CN claimed
WO-2004081020-A1 TRANSITION METAL COMPLEXES, ESPECIALLY IRON COMPLEXES, USED AS A CATALYST COMPONENT IN THE POLYMERISATION OF OLEFINS IC INNOVATIONS LTD (GB) 2004-09-23 WO claimed
US-6737486-B2 USING ORGANIC HALIDE OR SULFUR INITIATOR; MAINTAINING PROCESS CONTROL AND UNIFORMITY EASTMAN KODAK COMPANY 2004-05-18 US claimed
US-20040014910-A1 Novel polymerization process EASTMAN KODAK COMPANY 2004-01-22 US claimed
US-6310165-B1 VINYL MONOMER WITH ONIUM SALT TRANSITION METAL CAYALYST EASTMAN KODAK COMPANY 2001-10-30 US claimed
US-6306995-B1 CATALYTIC POLYMERIZATION WITH ONIUM CATALYSTS EASTMAN KODAK COMPANY 2001-10-23 US claimed
WO-2001068726-A1 ATOM TRANSFER RADICAL POLYMERISATION CATALYST BP CHEMICALS LIMITED (GB) 2001-09-20 WO claimed
US-3982942-A MANGANESE CARBONYL CATALYST ICI UNITED STATES INC. (US) 1976-09-28 US claimed
JP-62059267-A None JP disclosed
US-20250388592-A1 (AZA)SPIROHEPTANE DERIVATIVES FOR THE TREATMENT OF NEURODEGENERATIVE DISORDERS REMYND N.V. (BE) 2025-12-25 US disclosed
EP-4568968-A1 (AZA)SPIROHEPTANE DERIVATIVES FOR THE TREATMENT OF NEURODEGENERATIVE DISORDERS Remynd N.V. (BE) 2025-06-18 EP disclosed
US-20250163017-A1 LANTHIONINE C-LIKE PROTEIN 2 LIGANDS, CELLS PREPARED THEREWITH, AND THERAPIES USING SAME NIMMUNE BIOPHARMA, INC. (US) 2025-05-22 US disclosed
US-12145920-B2 Lanthionine c-like protein 2 ligands, cells prepared therewith, and therapies using same NIMMUNE BIOPHARMA, INC. (US) 2024-11-19 US disclosed
US-4025695-A LAMINATION EXXON RESEARCH AND ENGINEERING COMPANY (US) 1977-05-24 US disclosed
US-4010289-A METHOD OF MANUFACTURING SYNTHETIC RESIN FILM HAVING HIGH WRITABILITY AND PRINTABILITY SHOWA DENKO KABUSHIKI KAISHA (JA) 1977-03-01 US disclosed
US-3984465-A DIURETIC, SALURETIC AND URICOSURIC MERCK & CO., INC. (US) 1976-10-05 US disclosed
US-3982942-A MANGANESE CARBONYL CATALYST ICI UNITED STATES INC. (US) 1976-09-28 US disclosed
US-3860429-A PHOTOPOLYMERIZATION OF ETHYLENICALLY UNSATURATED ORGANIC COMPOUNDS ICI AMERICA INC 1975-01-14 US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (4 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20250163017-A1 LANTHIONINE C-LIKE PROTEIN 2 LIGANDS, CELLS PREPARED THEREWITH, AND THERAPIES USING SAME LCP2, LANCL2, SSB CES1 236/4885SRC 4349/4885TSHR 1609/4885
US-20060258867-A1 Transition metal complexes, especially iron complexes, used as a catalyst component in the polymerisation of olefins NR1I3, OPRD1, NR1I2 CES1 3707/4885SRC 1793/4885TSHR 705/4885
US-12145920-B2 Lanthionine c-like protein 2 ligands, cells prepared therewith, and therapies using same LCP2, LANCL2, SSB CES1 236/4885SRC 4349/4885TSHR 1609/4885
US-20250388592-A1 (AZA)SPIROHEPTANE DERIVATIVES FOR THE TREATMENT OF NEURODEGENERATIVE DISORDERS SNCA, CHRNA6, CHRNA5 CES1 568/4885SRC 4025/4885TSHR 1240/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.