Predicted protein targets (top 3)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MMP13 | P45452 | 20/20 | 0.59 |
| ▸ | SLC22A8 | Q8TCC7 | 1/20 | 0.54 |
| ▸ | MMP3 | P08254 | 1/20 | 0.52 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL3691303 | 0.89 | MMP13 (0.64) | MMP13SLC22A8MMP3 | |
| SCHEMBL8066370 | 0.89 | MMP13 (0.64) | MMP13SLC22A8MMP3 | |
| SCHEMBL3805364 | 0.85 | MMP13 (0.71) | MMP13SLC22A8MMP3 | |
| SCHEMBL3805358 | 0.85 | MMP13 (0.71) | MMP13SLC22A8MMP3 | |
| SCHEMBL8072489 | 0.85 | MMP13 (0.55) | MMP13SLC22A8 | |
| SCHEMBL8071049 | 0.84 | MMP13 (0.54) | MMP13SLC22A8MMP3 | |
| SCHEMBL3807119 | 0.83 | MMP13 (0.66) | MMP13SLC22A8 | |
| SCHEMBL8073496 | 0.83 | MMP13 (0.66) | MMP13SLC22A8 | |
| SCHEMBL3803469 | 0.82 | MMP13 (0.59) | MMP13SLC22A8MMP3 | |
| SCHEMBL3803463 | 0.82 | MMP13 (0.59) | MMP13SLC22A8MMP3 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2009016498-A1 | PYRIMIDINE AND PYRIDINE DERIVATIVES AND THEIR PHARMACEUTICAL USE AND COMPOSITIONS | PFIZER INC. (US) | 2009-02-05 | — | — | WO | disclosed |