SCHEMBL8067905

SCHEMBL8067905

c1ccc(COC[C@]2(OCc3ccccc3)OC[C@@H](OCc3ccccc3)[C@@H](OCc3ccccc3)[C@H]2OCc2ccccc2)cc1

nearest known ligand 0.46

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
BCHE P06276 4/20 0.46
ACHE P22303 2/20 0.46
CTSV O60911 1/20 0.36
CTSL P07711 1/20 0.36
CTSB P07858 1/20 0.36
CTSS P25774 1/20 0.36
CTSK P43235 1/20 0.36
CTSC P53634 1/20 0.36
CTSF Q9UBX1 1/20 0.36
PDE4D Q08499 1/20 0.36
TSHR P16473 1/20 0.35
TACR1 P25103 1/20 0.35
PSEN1 P49768 2/20 0.34
PSEN2 P49810 2/20 0.34
APH1B Q8WW43 2/20 0.34
NCSTN Q92542 2/20 0.34
APH1A Q96BI3 2/20 0.34
PSENEN Q9NZ42 2/20 0.34
PDPK1 O15530 1/20 0.34
MTOR P42345 1/20 0.34

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL8067902 0.86 BCHE (0.41) BCHEACHECTSVCTSLCTSB
SCHEMBL8074042 0.77 BCHE (0.40) BCHEACHECTSVCTSLCTSB
SCHEMBL10321618 0.76 BCHE (0.41) BCHEACHETACR1TAAR1
SCHEMBL7565726 0.75 BCHE (0.43) BCHEACHECTSVCTSLCTSB
SCHEMBL20819128 0.73 TAAR1 (0.39) BCHEACHECTSVCTSLCTSB
SCHEMBL5103512 0.72 BCHE (0.49) BCHEACHECTSVCTSLCTSB
SCHEMBL23705135 0.72 TSHR (0.35) BCHEACHECTSVCTSLCTSB
SCHEMBL23867782 0.71 BCHE (0.49) BCHEACHECTSVCTSLCTSB
SCHEMBL6551128 0.71 BCHE (0.47) BCHEACHECTSVCTSLCTSB
SCHEMBL6551134 0.71 BCHE (0.47) BCHEACHECTSVCTSLCTSB

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-0673947-B1 PSICOFURANOSE AND PSICOPYRANOSE DERIVATIVES SANKYO CO (JP) 2000-07-12 EP disclosed
EP-0673947-A1 PSICOFURANOSE AND PSICOPYRANOSE DERIVATIVES Sankyo Company Limited (JP) 1995-09-27 EP disclosed