SCHEMBL8067902

SCHEMBL8067902

OCC1(OCc2ccccc2)OC[C@@H](OCc2ccccc2)[C@@H](OCc2ccccc2)[C@H]1OCc1ccccc1

nearest known ligand 0.41

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
BCHE P06276 6/20 0.41
ACHE P22303 1/20 0.41
PDE4D Q08499 1/20 0.39
SLC6A2 P23975 1/20 0.38
PDPK1 O15530 1/20 0.38
MTOR P42345 1/20 0.38
CTSV O60911 1/20 0.36
CTSL P07711 1/20 0.36
CTSB P07858 1/20 0.36
CTSS P25774 1/20 0.36
CTSK P43235 1/20 0.36
CTSC P53634 1/20 0.36
CTSF Q9UBX1 1/20 0.36
PSEN1 P49768 2/20 0.35
PSEN2 P49810 2/20 0.35
APH1B Q8WW43 2/20 0.35
NCSTN Q92542 2/20 0.35
APH1A Q96BI3 2/20 0.35
PSENEN Q9NZ42 2/20 0.35
CYP2C9 P11712 1/20 0.32

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL8074042 0.88 BCHE (0.40) BCHEACHEPDE4DSLC6A2PDPK1
SCHEMBL8067905 0.86 BCHE (0.46) BCHEACHEPDE4DSLC6A2PDPK1
SCHEMBL7565726 0.78 BCHE (0.43) BCHEACHEPDE4DSLC6A2PDPK1
SCHEMBL16897692 0.72 GBA1 (0.39) PDE4DSLC6A2CYP2C9CYP2C19
SCHEMBL23867782 0.72 BCHE (0.49) BCHEACHEPDE4DSLC6A2PDPK1
SCHEMBL8068898 0.71 BCHE (0.39) BCHEACHESLC6A2PDPK1MTOR
SCHEMBL20960030 0.70 BCHE (0.42) BCHEACHECTSVCTSLCTSB
SCHEMBL22710225 0.70 SLC6A2 (0.58) BCHEACHEPDE4DSLC6A2PDPK1
SCHEMBL20193189 0.70 SLC6A2 (0.58) BCHEACHEPDE4DSLC6A2PDPK1
SCHEMBL24894599 0.70 SLC6A2 (0.58) BCHEACHEPDE4DSLC6A2PDPK1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-0673947-B1 PSICOFURANOSE AND PSICOPYRANOSE DERIVATIVES SANKYO CO (JP) 2000-07-12 EP disclosed
EP-0673947-A1 PSICOFURANOSE AND PSICOPYRANOSE DERIVATIVES Sankyo Company Limited (JP) 1995-09-27 EP disclosed