Known targets — ChEMBL curated mechanism
ACHECHRM1CHRM3CHRNA1CHRNB1CHRNDCHRNECHRNG
The experimentally established mechanism targets of Iodide. The predicted profile below is derived independently by chemical similarity — agreement is a validation signal, a miss is honest.
Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAPT | P10636 | 8/20 | 0.87 |
| ▸ | KMT2A | Q03164 | 7/20 | 0.87 |
| ▸ | MEN1 | O00255 | 6/20 | 0.87 |
| ▸ | ALDH1A1 | P00352 | 6/20 | 0.87 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.87 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.87 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.87 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.87 |
| ▸ | ALOX12 | P18054 | 1/20 | 0.87 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.87 |
| ▸ | CTNNB1 | P35222 | 1/20 | 0.87 |
| ▸ | HTT | P42858 | 5/20 | 0.67 |
| ▸ | LMNA | P02545 | 4/20 | 0.67 |
| ▸ | THRB | P10828 | 4/20 | 0.67 |
| ▸ | POLB | P06746 | 4/20 | 0.67 |
| ▸ | MAPK1 | P28482 | 3/20 | 0.67 |
| ▸ | SMN1; SMN2 | Q16637 | 3/20 | 0.67 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.67 |
| ▸ | BLM | P54132 | 2/20 | 0.67 |
| ▸ | TDP1 | Q9NUW8 | 2/20 | 0.67 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Iodide SCHEMBL9768656 | 1.00 | MAPT (0.87) | MAPTKMT2AMEN1ALDH1A1CYP1A2 | |
| Perchlorate SCHEMBL11638443 | 0.94 | MAPT (0.78) | MAPTKMT2AMEN1ALDH1A1CYP1A2 | |
| Iodide SCHEMBL5329489 | 0.93 | KMT2A (1.00) | MAPTKMT2AMEN1ALDH1A1CYP1A2 | |
| Iodide SCHEMBL5329486 | 0.93 | KMT2A (1.00) | MAPTKMT2AMEN1ALDH1A1CYP1A2 | |
| Iodide SCHEMBL9437119 | 0.92 | KMT2A (0.98) | MAPTKMT2AMEN1ALDH1A1CYP1A2 | |
| Iodide SCHEMBL9437122 | 0.92 | KMT2A (0.98) | MAPTKMT2AMEN1ALDH1A1CYP1A2 | |
| SCHEMBL12821744 | 0.92 | KMT2A (0.98) | MAPTKMT2AMEN1ALDH1A1CYP1A2 | |
| SCHEMBL12821746 | 0.92 | KMT2A (0.98) | MAPTKMT2AMEN1ALDH1A1CYP1A2 | |
| Iodide SCHEMBL20856302 | 0.91 | MAPT (0.73) | MAPTKMT2AMEN1ALDH1A1CYP1A2 | |
| Iodide SCHEMBL20856301 | 0.91 | MAPT (0.73) | MAPTKMT2AMEN1ALDH1A1CYP1A2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 24 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0730008-B1 | Method of synthesizing dyes and precursor compounds therefor | EASTMAN KODAK CO (US) | 2000-06-14 | — | — | EP | disclosed |
| US-5679795-A | Method of synthesizing dyes and precursor compounds therefor | EASTMAN KODAK COMPANY (US) | 1997-10-21 | — | — | US | disclosed |
| EP-0730008-A2 | Method of synthesizing dyes and precursor compounds therefor | EASTMAN KODAK COMPANY (US) | 1996-09-04 | — | — | EP | disclosed |
| US-5032500-A | Adding sensitizing dye containing for inhibitor after grain formation and before ripening | FUJI PHOTO FILM CO., LTD. (JP) | 1991-07-16 | — | — | US | disclosed |
| EP-0136847-B1 | PHOTOGRAPHICALLY USEFUL CHALCOGENAZOLYLIDENE AND CHALCOGENAZOLIUM DYES AND METHODS FOR THEIR PREPARATION | EASTMAN KODAK COMPANY (a New Jersey corporation) (US) | 1990-01-17 | — | — | EP | disclosed |
| US-4874866-A | AROMATIC TELLURIUM-NITROGEN COMPOUNDS; DYES | EASTMAN KODAK COMPANY (US) | 1989-10-17 | — | — | US | disclosed |
| US-4855213-A | SPECTRA SENSITIZERS | EASTMAN KODAK COMPANY (US) | 1989-08-08 | — | — | US | disclosed |
| US-4839260-A | Novel polymethine dyes and UV absorbers and imaging materials for their use | EASTMAN KODAK COMPANY (US) | 1989-06-13 | — | — | US | disclosed |
| US-4839274-A | Novel polymethine dyes and UV absorbers containing a triarylborylisocyano group and imaging compositions containing these dyes | EASTMAN KODAK COMPANY (US) | 1989-06-13 | — | — | US | disclosed |
| US-4831136-A | Oxatellurazolium and oxatellurazinium compounds | EASTMAN KODAK COMPANY (US) | 1989-05-16 | — | — | US | disclosed |
| EP-0297872-A2 | Novel polymethine dyes and UV absorbers and imaging materials for their use | EASTMAN KODAK COMPANY (a New Jersey corporation) (US) | 1989-01-04 | — | — | EP | disclosed |
| US-4713316-A | INFRARED SENSITIZING DYES, MOBILE DYE PRECURSORS, ALKALI, SILVER HALIDE EMULSION | FUJI PHOTO FILM CO., LTD. (JP) | 1987-12-15 | — | — | US | disclosed |
| US-4576905-A | Photographically useful chalcogenazoles, chalcogenazolines, and chalcogenazolinium and chalcogenazolium salts | EASTMAN KODAK COMPANY (US) | 1986-03-18 | — | — | US | disclosed |
| EP-0136847-A2 | Photographically useful chalcogenazolylidene and chalcogenazolium dyes and methods for their preparation | EASTMAN KODAK COMPANY (a New Jersey corporation) (US) | 1985-04-10 | — | — | EP | disclosed |
| US-4375508-A | ACETHYLENIC HYDROCARBON CHAIN | EASTMAN KODAK COMPANY (US) | 1983-03-01 | — | — | US | disclosed |
| US-4283488-A | SILVER HALIDE EMULSIONS | EASTMAN KODAK COMPANY (US) | 1981-08-11 | — | — | US | disclosed |
| US-4232115-A | MEROCYANINE, OXONOL, AND STYRYL DYES | E. I. DU PONT DE NEMOURS AND COMPANY (US) | 1980-11-04 | — | — | US | disclosed |
| US-4197080-A | Radiation-cleavable nondiffusible compounds and photographic elements and processes employing them | EASTMAN KODAK COMPANY (US) | 1980-04-08 | — | — | US | disclosed |
| US-RE29168-E | HEAT SENSITIVE, ANTIHALATION LAYER | EASTMAN KODAK COMPANY (US) | 1977-04-05 | — | — | US | disclosed |
| US-4003750-A | METHINE DYES | EASTMAN KODAK COMPANY (US) | 1977-01-18 | — | — | US | disclosed |