Known targets — ChEMBL curated mechanism
ACHECHRM1CHRM3CHRNA1CHRNB1CHRNDCHRNECHRNG
The experimentally established mechanism targets of Iodide. The predicted profile below is derived independently by chemical similarity — agreement is a validation signal, a miss is honest.
Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KMT2A | Q03164 | 9/20 | 1.00 |
| ▸ | MAPT | P10636 | 8/20 | 1.00 |
| ▸ | MEN1 | O00255 | 8/20 | 1.00 |
| ▸ | ALDH1A1 | P00352 | 6/20 | 1.00 |
| ▸ | ALOX12 | P18054 | 2/20 | 1.00 |
| ▸ | CTNNB1 | P35222 | 2/20 | 1.00 |
| ▸ | CYP1A2 | P05177 | 1/20 | 1.00 |
| ▸ | CYP3A4 | P08684 | 1/20 | 1.00 |
| ▸ | CYP2D6 | P10635 | 1/20 | 1.00 |
| ▸ | CYP2C9 | P11712 | 1/20 | 1.00 |
| ▸ | CYP2C19 | P33261 | 1/20 | 1.00 |
| ▸ | HTT | P42858 | 6/20 | 0.77 |
| ▸ | LMNA | P02545 | 5/20 | 0.77 |
| ▸ | BLM | P54132 | 5/20 | 0.77 |
| ▸ | THRB | P10828 | 4/20 | 0.77 |
| ▸ | KDM4E | B2RXH2 | 4/20 | 0.77 |
| ▸ | POLB | P06746 | 4/20 | 0.77 |
| ▸ | MAPK1 | P28482 | 3/20 | 0.77 |
| ▸ | SMN1; SMN2 | Q16637 | 3/20 | 0.77 |
| ▸ | TDP1 | Q9NUW8 | 2/20 | 0.77 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Iodide SCHEMBL5329486 | 1.00 | KMT2A (1.00) | KMT2AMAPTMEN1ALDH1A1ALOX12 | |
| Iodide SCHEMBL9437119 | 0.99 | KMT2A (0.98) | KMT2AMAPTMEN1ALDH1A1ALOX12 | |
| Iodide SCHEMBL9437122 | 0.99 | KMT2A (0.98) | KMT2AMAPTMEN1ALDH1A1ALOX12 | |
| SCHEMBL12821744 | 0.99 | KMT2A (0.98) | KMT2AMAPTMEN1ALDH1A1ALOX12 | |
| SCHEMBL12821746 | 0.99 | KMT2A (0.98) | KMT2AMAPTMEN1ALDH1A1ALOX12 | |
| SCHEMBL13646783 | 0.98 | KMT2A (0.96) | KMT2AMAPTMEN1ALDH1A1ALOX12 | |
| Perchlorate SCHEMBL10521396 | 0.95 | MAPT (0.90) | KMT2AMAPTMEN1ALDH1A1ALOX12 | |
| Iodide SCHEMBL9768656 | 0.93 | MAPT (0.87) | KMT2AMAPTMEN1ALDH1A1ALOX12 | |
| Iodide SCHEMBL8067949 | 0.93 | MAPT (0.87) | KMT2AMAPTMEN1ALDH1A1ALOX12 | |
| Perchlorate SCHEMBL11638443 | 0.88 | MAPT (0.78) | KMT2AMAPTMEN1ALDH1A1ALOX12 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 12 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-10316371-B2 | Screening methods for identifying specific Staphylococcus aureus inhibitors | TRANA DISCOVERY, INC. (US) | 2019-06-11 | — | — | US | disclosed |
| US-20140163037-A1 | SCREENING METHODS FOR IDENTIFYING SPECIFIC STAPHYLOCOCCUS AUREUS INHIBITORS | TRANA DISCOVERY, INC. (US) | 2014-06-12 | — | — | US | disclosed |
| EP-2691542-A1 | SCREENING METHODS FOR IDENTIFYING SPECIFIC STAPHYLOCOCCUS AUREUS INHIBITORS | Trana Discovery, Inc. (US) | 2014-02-05 | — | — | EP | disclosed |
| WO-2012135416-A1 | SCREENING METHODS FOR IDENTIFYING SPECIFIC STAPHYLOCOCCUS AUREUS INHIBITORS | TRANA DISCOVERY, INC. (US) | 2012-10-04 | — | — | WO | disclosed |
| WO-2007128691-A1 | HIGH CAPACITY OPTICAL STORAGE MEDIA COMPRISING ORGANOMETALLIC ION PAIRS | CIBA HOLDING INC. (CH) | 2007-11-15 | — | — | WO | disclosed |
| US-4855213-A | SPECTRA SENSITIZERS | EASTMAN KODAK COMPANY (US) | 1989-08-08 | — | — | US | disclosed |
| US-4839260-A | Novel polymethine dyes and UV absorbers and imaging materials for their use | EASTMAN KODAK COMPANY (US) | 1989-06-13 | — | — | US | disclosed |
| US-4839274-A | Novel polymethine dyes and UV absorbers containing a triarylborylisocyano group and imaging compositions containing these dyes | EASTMAN KODAK COMPANY (US) | 1989-06-13 | — | — | US | disclosed |
| EP-0297871-A2 | Novel polymethine dyes and UV absorbers and imaging materials for their use | EASTMAN KODAK COMPANY (a New Jersey corporation) (US) | 1989-01-04 | — | — | EP | disclosed |
| EP-0297872-A2 | Novel polymethine dyes and UV absorbers and imaging materials for their use | EASTMAN KODAK COMPANY (a New Jersey corporation) (US) | 1989-01-04 | — | — | EP | disclosed |
| EP-0297873-A2 | Novel polymethine dyes and imaging compositions | EASTMAN KODAK COMPANY (a New Jersey corporation) (US) | 1989-01-04 | — | — | EP | disclosed |
| US-RE29168-E | HEAT SENSITIVE, ANTIHALATION LAYER | EASTMAN KODAK COMPANY (US) | 1977-04-05 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20140163037-A1 | SCREENING METHODS FOR IDENTIFYING SPECIFIC STAPHYLOCOCCUS AUREUS INHIBITORS | NSUN3, RNGTT, TRMT1 | KMT2A 1190/4885MAPT 2009/4885MEN1 3734/4885 |
| US-10316371-B2 | Screening methods for identifying specific Staphylococcus aureus inhibitors | NSUN3, RNGTT, TRMT1 | KMT2A 1190/4885MAPT 2009/4885MEN1 3734/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.