Predicted protein targets (top 3)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MMP13 | P45452 | 18/20 | 0.69 |
| ▸ | ROCK2 | O75116 | 1/20 | 0.41 |
| ▸ | ROCK1 | Q13464 | 1/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL3757092 | 1.00 | MMP13 (0.69) | MMP13ROCK2ROCK1 | |
| SCHEMBL8070962 | 1.00 | MMP13 (0.69) | MMP13ROCK2ROCK1 | |
| SCHEMBL8069587 | 0.88 | MMP13 (0.72) | MMP13 | |
| SCHEMBL8068867 | 0.88 | MMP13 (0.72) | MMP13 | |
| SCHEMBL8065862 | 0.88 | MMP13 (0.72) | MMP13ROCK2ROCK1 | |
| SCHEMBL8067050 | 0.83 | MMP13 (0.75) | MMP13 | |
| SCHEMBL8071412 | 0.83 | MMP13 (0.74) | MMP13 | |
| SCHEMBL8055109 | 0.82 | MMP13 (1.00) | MMP13 | |
| SCHEMBL3805009 | 0.82 | MMP13 (1.00) | MMP13 | |
| SCHEMBL3644767 | 0.82 | MMP13 (1.00) | MMP13 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2009016498-A1 | PYRIMIDINE AND PYRIDINE DERIVATIVES AND THEIR PHARMACEUTICAL USE AND COMPOSITIONS | PFIZER INC. (US) | 2009-02-05 | — | — | WO | disclosed |