SCHEMBL8068413

SCHEMBL8068413

C=CCN(CC=C)C(=O)CCCCC(=O)N(CC=C)CC=C

nearest known ligand 0.91

Predicted protein targets (top 15)

geneUniProtsupporting neighboursconfidence
ALDH1A1 P00352 6/20 0.91
SMN1; SMN2 Q16637 2/20 0.44
LMNA P02545 4/20 0.42
POLB P06746 1/20 0.41
MAPT P10636 3/20 0.38
ABCC4 O15439 1/20 0.38
TSHR P16473 1/20 0.38
RAB9A P51151 1/20 0.33
HPGD P15428 1/20 0.33
ALOX12 P18054 1/20 0.33
CCR6 P51684 1/20 0.33
KDM4E B2RXH2 1/20 0.33
MEN1 O00255 1/20 0.33
KMT2A Q03164 1/20 0.33
DPP4 P27487 1/20 0.33

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL7629952 0.98 ALDH1A1 (0.86) ALDH1A1SMN1; SMN2LMNAPOLBMAPT
SCHEMBL13630658 0.98 ALDH1A1 (0.86) ALDH1A1SMN1; SMN2LMNAPOLBMAPT
SCHEMBL15049827 0.98 ALDH1A1 (0.86) ALDH1A1SMN1; SMN2LMNAPOLBMAPT
SCHEMBL316404 0.91 ALDH1A1 (0.76) ALDH1A1SMN1; SMN2LMNAPOLBMAPT
SCHEMBL16350574 0.90 ALDH1A1 (0.81) ALDH1A1SMN1; SMN2LMNAPOLBMAPT
SCHEMBL17141436 0.89 ALDH1A1 (0.73) ALDH1A1SMN1; SMN2LMNAPOLBMAPT
SCHEMBL568962 0.89 ALDH1A1 (0.73) ALDH1A1LMNATSHRMEN1KMT2A
SCHEMBL8106845 0.89 ALDH1A1 (0.79) ALDH1A1SMN1; SMN2LMNAPOLBMAPT
SCHEMBL11564777 0.88 ALDH1A1 (0.70) ALDH1A1LMNATSHRMEN1KMT2A
SCHEMBL570411 0.88 ALDH1A1 (0.70) ALDH1A1LMNATSHRMEN1KMT2A

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 15 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-4460748-A Process for crosslinking and, if desired, foaming natural or synthetic homo- and/or copolymers LUPEROX GMBH (DE) 1984-07-17 US claimed
EP-0273274-B1 Degradation of polyethylene by means of agents generating free radicals ATOCHEM ELF DEUTSCHLAND (DE) 2000-07-12 EP disclosed
EP-0273274-A2 Degradation of polyethylene by means of agents generating free radicals Elf Atochem Deutschland GmbH (DE) 1988-07-06 EP disclosed
US-4683248-A PEROXIDES AND UNSATURATED COMPOUNDS LUPEROX GMBH (DE) 1987-07-28 US disclosed
EP-0180789-A1 Cross-linking of styrene polymers Luperox GmbH (DE) 1986-05-14 EP disclosed
EP-0073038-B1 PROCESS FOR CROSS-LINKING AND IF REQUIRED FOAMING NATURAL OR SYNTHETIC HOMO- AND/OR COPOLYMERS Luperox GmbH (DE) 1986-01-02 EP disclosed
US-4498957-A Aromatic polyamide paper-like sheet and processes for producing the same TEIJIN LIMITED (JP) 1985-02-12 US disclosed
US-4460748-A Process for crosslinking and, if desired, foaming natural or synthetic homo- and/or copolymers LUPEROX GMBH (DE) 1984-07-17 US disclosed
EP-0087234-A1 Ashless dispersant compounds, their preparation, and their use in providing dispersancy in lubricating oils or liquid fuels EDWIN COOPER INC. (US) 1983-08-31 EP disclosed
EP-0019113-B1 AROMATIC POLYAMIDE PAPER-LIKE SHEET AND PROCESSES FOR PRODUCING THE SAME TEIJIN LIMITED (JP) 1983-04-13 EP disclosed
EP-0073435-A2 Process for curing and optionally foaming polypropylene Luperox GmbH (DE) 1983-03-09 EP disclosed
EP-0073038-A1 Process for cross-linking and if required foaming natural or synthetic homo- and/or copolymers Luperox GmbH (DE) 1983-03-02 EP disclosed
EP-0019113-A1 Aromatic polyamide paper-like sheet and processes for producing the same TEIJIN LIMITED (JP) 1980-11-26 EP disclosed
US-4150237-A INTERMEDIATES IN THE FORMATION OF EPOXIDES THE DOW CHEMICAL COMPANY (US) 1979-04-17 US disclosed
US-4126746-A Halohydrin thioethers and method of preparation THE DOW CHEMICAL COMPANY (US) 1978-11-21 US disclosed