SCHEMBL8068415

SCHEMBL8068415

COC(=O)c1ccc(O)c(NS(C)(=O)=O)c1

nearest known ligand 0.72

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
KDM4E B2RXH2 3/20 0.72
SMN1; SMN2 Q16637 2/20 0.72
HSD17B10 Q99714 2/20 0.72
CA12 O43570 2/20 0.59
CA1 P00915 2/20 0.59
CA2 P00918 2/20 0.59
CA7 P43166 2/20 0.59
CA9 Q16790 2/20 0.59
CA14 Q9ULX7 2/20 0.59
XDH P47989 1/20 0.59
POLB P06746 1/20 0.56
ADRB3 P13945 5/20 0.56
ALDH1A1 P00352 4/20 0.53
MAPT P10636 2/20 0.53
HPGD P15428 2/20 0.53
HTT P42858 2/20 0.53
MEN1 O00255 1/20 0.53
LMNA P02545 1/20 0.53
TP53 P04637 1/20 0.53
ALOX15 P16050 1/20 0.53

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL3237044 0.87 KDM4E (0.77) KDM4ESMN1; SMN2HSD17B10CA12CA1
SCHEMBL8959050 0.85 HPGD (0.62) KDM4ESMN1; SMN2HSD17B10CA12CA1
SCHEMBL4175701 0.84 KDM4E (0.72) KDM4ESMN1; SMN2HSD17B10POLBALDH1A1
SCHEMBL966589 0.83 ADRB3 (0.58) KDM4ESMN1; SMN2HSD17B10ADRB3ALDH1A1
SCHEMBL15894590 0.83 ADRB3 (0.58) KDM4ESMN1; SMN2HSD17B10CA12CA1
SCHEMBL5440367 0.83 KDM4E (0.70) KDM4ESMN1; SMN2HSD17B10CA12CA1
SCHEMBL15754401 0.83 KDM4E (0.70) KDM4ESMN1; SMN2HSD17B10CA12CA1
SCHEMBL4952535 0.83 KDM4E (0.70) KDM4ESMN1; SMN2HSD17B10CA12CA1
SCHEMBL14389382 0.83 KDM4E (0.70) KDM4ESMN1; SMN2HSD17B10POLBALDH1A1
SCHEMBL5071184 0.83 SMN1; SMN2 (0.70) KDM4ESMN1; SMN2HSD17B10POLBALDH1A1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 9 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-6162598-A Silver halide photographic element containing improved yellow dye-forming coupler EASTMAN KODAK COMPANY (US) 2000-12-19 US disclosed
EP-1014187-A1 Silver halide photographic element containing improved yellow dye-forming coupler EASTMAN KODAK COMPANY (US) 2000-06-28 EP disclosed
EP-0600563-B1 Yellow couplers having an aryloxy coupling-off group which contains an orthopolarizable functional group EASTMAN KODAK CO (US) 1999-03-24 EP disclosed
US-5427898-A Dioxanyl and andamantanyl acetanilide-type couplers EASTMAN KODAK COMPANY (US) 1995-06-27 US disclosed
EP-0600563-A1 Yellow couplers having an aryloxy coupling-off group which contains an orthopolarizable functional group EASTMAN KODAK COMPANY (US) 1994-06-08 EP disclosed
EP-0080355-B2 Photographic elements containing aryloxy substituted photographic couplers EASTMAN KODAK CO (US) 1994-04-06 EP disclosed
EP-0080355-B1 PHOTOGRAPHIC ELEMENTS CONTAINING ARYLOXY SUBSTITUTED PHOTOGRAPHIC COUPLERS EASTMAN KODAK COMPANY (a New Jersey corporation) (US) 1985-05-08 EP disclosed
US-4401752-A Aryloxy substituted photographic couplers and photographic elements and processes employing same EASTMAN KODAK COMPANY (US) 1983-08-30 US disclosed
EP-0080355-A1 Photographic elements containing aryloxy substituted photographic couplers EASTMAN KODAK COMPANY (a New Jersey corporation) (US) 1983-06-01 EP disclosed