SCHEMBL8959050

SCHEMBL8959050

CCOC(=O)c1ccc(O)c(NS(C)(=O)=O)c1

nearest known ligand 0.62

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
HPGD P15428 3/20 0.62
RECQL P46063 1/20 0.62
CA1 P00915 3/20 0.60
CA2 P00918 3/20 0.60
CA12 O43570 2/20 0.60
CA7 P43166 2/20 0.60
CA9 Q16790 2/20 0.60
CA14 Q9ULX7 2/20 0.60
HSD17B2 P37059 1/20 0.55
ADRB3 P13945 3/20 0.54
KDM4E B2RXH2 3/20 0.54
HSD17B10 Q99714 2/20 0.54
SMN1; SMN2 Q16637 1/20 0.54
TSHR P16473 1/20 0.49
ADRA2A P08913 2/20 0.49
ADRA2B P18089 2/20 0.49
ADRA2C P18825 2/20 0.49
ADRA1A P35348 2/20 0.49
ESR1 P03372 1/20 0.49
ESR2 Q92731 1/20 0.49

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL8959046 0.86 HPGD (0.67) HPGDRECQLCA1CA2CA12
SCHEMBL8068415 0.85 KDM4E (0.72) HPGDCA1CA2CA12CA7
SCHEMBL14799282 0.83 HPGD (0.59) HPGDRECQLCA1CA2HSD17B2
SCHEMBL8887638 0.82 PTGER4 (0.64) HPGDRECQLCA1CA2CA12
SCHEMBL13028646 0.81 NHERF1 (0.68) HPGDCA1CA2CA12CA7
SCHEMBL8888554 0.80 HPGD (0.56) HPGDRECQLCA1CA2CA12
SCHEMBL8958864 0.79 CA12 (0.64) HPGDCA1CA2CA12CA7
Hydrochloric Acid SCHEMBL8887790 0.79 HPGD (0.54) HPGDRECQLCA1CA2CA12
SCHEMBL15894590 0.79 ADRB3 (0.58) CA1CA2CA12CA7CA9
SCHEMBL966589 0.79 ADRB3 (0.58) HPGDADRB3KDM4EHSD17B10SMN1; SMN2

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 6 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-0436938-B1 Silver halide color photographic material containing yellow colored cyan coupler FUJI PHOTO FILM CO LTD (JP) 1996-06-19 EP disclosed
US-5498513-A BENZOTRIAZOLE DIR COUPLERS FUJI PHOTO FILM CO., LTD. (JP) 1996-03-12 US disclosed
EP-0451526-B1 Silver halide colour photographic materials FUJI PHOTO FILM CO LTD (JP) 1996-01-24 EP disclosed
CN-1057343-A SILVER HALIDE COLOR PHOTOGRAPHIC MATERIALS FUJI PHOTO FILM CO LTD (JP) 1991-12-25 CN disclosed
EP-0451526-A2 Silver halide colour photographic materials FUJI PHOTO FILM CO., LTD. (JP) 1991-10-16 EP disclosed
US-4927743-A Silver halide photographic light-sensitive materials having specified coupler, dir coupler and silver coverage FUJI PHOTO FILM CO., LTD. (JP) 1990-05-22 US disclosed