Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CYP2C19 | P33261 | 2/20 | 0.44 |
| ▸ | HIF1A | Q16665 | 2/20 | 0.44 |
| ▸ | TSHR | P16473 | 2/20 | 0.44 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.44 |
| ▸ | HMGCR | P04035 | 1/20 | 0.41 |
| ▸ | CHRM1 | P11229 | 1/20 | 0.41 |
| ▸ | TBXA2R | P21731 | 1/20 | 0.41 |
| ▸ | ADRA1A | P35348 | 1/20 | 0.41 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.36 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.35 |
| ▸ | FFAR1 | O14842 | 1/20 | 0.35 |
| ▸ | CPT2 | P23786 | 1/20 | 0.35 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.35 |
| ▸ | MEN1 | O00255 | 1/20 | 0.32 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.32 |
| ▸ | THRB | P10828 | 1/20 | 0.32 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.32 |
| ▸ | FFAR3 | O14843 | 1/20 | 0.32 |
| ▸ | SLC13A5 | Q86YT5 | 2/20 | 0.31 |
| ▸ | KDM4C | Q9H3R0 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL1547881 | 0.86 | CYP2C19 (0.46) | CYP2C19HIF1ATSHRCYP2D6HMGCR | |
| SCHEMBL27902708 | 0.84 | CYP2C19 (0.44) | CYP2C19HIF1ATSHRCYP2D6HMGCR | |
| SCHEMBL20912559 | 0.84 | CYP2C19 (0.44) | CYP2C19HIF1ATSHRCYP2D6HMGCR | |
| SCHEMBL5030692 | 0.84 | CYP2C19 (0.44) | CYP2C19HIF1ATSHRCYP2D6HMGCR | |
| SCHEMBL10621210 | 0.84 | CYP2C19 (0.44) | CYP2C19HIF1ATSHRCYP2D6HMGCR | |
| SCHEMBL28887606 | 0.84 | CYP2C19 (0.44) | CYP2C19HIF1ATSHRCYP2D6HMGCR | |
| Ammonia Solution, Strong SCHEMBL19976105 | 0.84 | CYP2C19 (0.44) | CYP2C19HIF1ATSHRCYP2D6HMGCR | |
| Bicarbonate SCHEMBL18954885 | 0.84 | CYP2C19 (0.44) | CYP2C19HIF1ATSHRCYP2D6HMGCR | |
| SCHEMBL8352054 | 0.84 | CYP2C19 (0.44) | CYP2C19HIF1ATSHRCYP2D6HMGCR | |
| SCHEMBL1772430 | 0.83 | THRB (0.37) | CYP2C19HIF1ATSHRCYP2D6HMGCR |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2009064071-A1 | CONTROLLED DRUG CARRIER FOR DELIVERYING SILDENAFIL CITRATE TRANSDERMALLY AND PATCH CONTAINING THE SAME | KYUNGPOOK NATIONAL UNIVERSITY INDUSTRY ACADEMIC COOPERATION FOUNDATION (KR) | 2009-05-22 | — | — | WO | disclosed |