⚠ Novel chemotype — no close known analogue (best Tanimoto < 0.3). Unexplored chemical space relative to ChEMBL.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8011959 | 0.77 | — | — | |
| Hydrochloric Acid SCHEMBL7527925 | 0.74 | TSHR (0.31) | — | |
| SCHEMBL2101208 | 0.74 | — | — | |
| SCHEMBL2103823 | 0.74 | — | — | |
| SCHEMBL10594695 | 0.74 | — | — | |
| SCHEMBL29197130 | 0.74 | — | — | |
| Hydrochloric Acid SCHEMBL28462379 | 0.72 | THRB (0.30) | — | |
| SCHEMBL2104091 | 0.72 | — | — | |
| SCHEMBL29114747 | 0.72 | — | — | |
| SCHEMBL3226599 | 0.72 | — | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 33 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-106831827-B | A kind of isolation and purification method of eldisine | 广州白云山汉方现代药业有限公司 | 2019-03-29 | — | — | CN | claimed |
| CN-106831827-A | A kind of isolation and purification method of eldisine | 广州白云山汉方现代药业有限公司 | 2017-06-13 | — | — | CN | claimed |
| CN-101270086-A | Sulfonation technique for isoliensinine, arrhythmia resistant function of products produced thereby | YANG PAN (CN) | 2008-09-24 | — | — | CN | claimed |
| CN-109358151-B | Thin-layer chromatography detection method for 1, 4-butanediamine impurity in L-2-amino-5-guanidino valeric acid raw material | 广东盛泰华生物制药有限公司 | 2021-01-05 | — | — | CN | disclosed |
| CN-110366434-A | Functionalized poly (fumaric acid acrylic ester) polymer prepared using Mg catalyst by ring-opening polymerisation | 阿克伦大学 | 2019-10-22 | — | — | CN | disclosed |
| CN-106831827-B | A kind of isolation and purification method of eldisine | 广州白云山汉方现代药业有限公司 | 2019-03-29 | — | — | CN | disclosed |
| CN-106831827-B | A kind of isolation and purification method of eldisine | 广州白云山汉方现代药业有限公司 | 2019-03-29 | — | — | CN | disclosed |
| CN-109358151-A | The thin-layered chromatography detection method of 1,4- butanediamine impurity in a kind of L-Arginine raw material | 广东盛泰华生物制药有限公司 | 2019-02-19 | — | — | CN | disclosed |
| CN-106831827-A | A kind of isolation and purification method of eldisine | 广州白云山汉方现代药业有限公司 | 2017-06-13 | — | — | CN | disclosed |
| CN-104961765-B | A kind of preparation method of the phosphatide with phosphatidyl-ethanolamine as principal component | 广州白云山汉方现代药业有限公司 | 2017-06-13 | — | — | CN | disclosed |
| CN-106831827-A | A kind of isolation and purification method of eldisine | 广州白云山汉方现代药业有限公司 | 2017-06-13 | — | — | CN | disclosed |
| US-4405789-A | ANTICONVULSANT, ANTIANXIETY | PHARMINDUSTRIE (FR) | 1983-09-20 | — | — | US | disclosed |
| US-4402961-A | Derivatives of 1-(2-,3- or 4-quinolyl)-2- or -3-(2- or 3-piperidyl or -pyrrolidinyl) ethanone or propanone, and their utilization as antiarrhythmics, anticonvulsivants and for the treatment of anxiety | PHARMINDUSTRIE (FR) | 1983-09-06 | — | — | US | disclosed |
| US-4377691-A | Process for the preparation of 1-(4-hydroxyphenyl)-2-(4-benzylpiperidino)-1-propanol and acid-addition salts thereof | KABUSHIKI KAISHA COSMOS ENTERPRISE (JP) | 1983-03-22 | — | — | US | disclosed |
| US-4357337-A | PIPERIDINYLALKYL DERIVATIVES | PHARMINDUSTRIE (FR) | 1982-11-02 | — | — | US | disclosed |
| US-4299835-A | ANXIOLYTICS | PHARMINDUSTRIE (FR) | 1981-11-10 | — | — | US | disclosed |
| US-4237139-A | TRANQUILIZERS, ANTIDEPRESSANTS | PHARMINDUSTRIE (FR) | 1980-12-02 | — | — | US | disclosed |
| US-4167638-A | Process for production of 8-NHR quinolines | THE UNITED STATES OF AMERICA AS REPRESENTED BY THE SECRETARY OF THE ARMY (US) | 1979-09-11 | — | — | US | disclosed |
| US-4042682-A | EXTRACTED FROM MAMMALIAN BRAINS BY MORPHINE-SPECIFIC ANTIBODIES | HOFFMANN-LA ROCHE INC. (US) | 1977-08-16 | — | — | US | disclosed |
| US-3947456-A | ANTIDEPRESSANTS | HOFFMAN-LA ROCHE INC. (US) | 1976-03-30 | — | — | US | disclosed |