SCHEMBL8068615

SCHEMBL8068615

C=C(C)C(=O)OC.C=C(CCC)C(=O)O

nearest known ligand 0.58

Predicted protein targets (top 19)

geneUniProtsupporting neighboursconfidence
ALDH1A1 P00352 3/20 0.58
TSHR P16473 4/20 0.39
THRB P10828 2/20 0.36
HDAC3 O15379 2/20 0.34
HDAC1 Q13547 2/20 0.34
HDAC2 Q92769 2/20 0.34
HDAC8 Q9BY41 2/20 0.34
FFAR3 O14843 1/20 0.34
FNTA P49354 1/20 0.32
FNTB P49356 1/20 0.32
PGGT1B P53609 1/20 0.32
EGLN1 Q9GZT9 1/20 0.31
ALOX15 P16050 1/20 0.31
HSD17B10 Q99714 1/20 0.31
HDAC6 Q9UBN7 1/20 0.31
CES2 O00748 1/20 0.31
CES1 P23141 1/20 0.31
TET2 Q6N021 1/20 0.31
CTSD P07339 1/20 0.30

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
Trimethylammonium SCHEMBL5669608 0.95 ALDH1A1 (0.52) ALDH1A1TSHRTHRBHDAC3HDAC1
SCHEMBL16262531 0.89 ALDH1A1 (0.54) ALDH1A1TSHRTHRBFNTAFNTB
SCHEMBL2196941 0.89 ALDH1A1 (0.54) ALDH1A1TSHRTHRBFNTAFNTB
SCHEMBL11706141 0.88 ALDH1A1 (0.62) ALDH1A1TSHRTHRBHDAC3HDAC1
SCHEMBL6413754 0.87 ALDH1A1 (0.52) ALDH1A1TSHRTHRBFNTAFNTB
Methacrylic Acid SCHEMBL7638298 0.87 ALDH1A1 (0.52) ALDH1A1TSHRTHRBFNTAFNTB
Trimethylammonium SCHEMBL6326203 0.86 ALDH1A1 (0.43) ALDH1A1TSHRTHRBEGLN1
Trimethylammonium SCHEMBL7355812 0.86 ALDH1A1 (0.43) ALDH1A1TSHRTHRBEGLN1
Trimethylammonium SCHEMBL7354581 0.86 ALDH1A1 (0.43) ALDH1A1TSHRTHRBEGLN1
SCHEMBL20357568 0.86 TSHR (0.50) ALDH1A1TSHRTHRBFNTAFNTB

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-6040009-A SOLVENTS, POLYESTER RESIN, STAR OLIGOMER AND CURING AGENTS MAZDA MOTOR CORPORATION (JP) 2000-03-21 US disclosed