Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | NR4A2 | P43354 | 2/20 | 0.49 |
| ▸ | SOS2 | Q07890 | 1/20 | 0.49 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.44 |
| ▸ | MAPT | P10636 | 4/20 | 0.43 |
| ▸ | GAA | P10253 | 2/20 | 0.43 |
| ▸ | ATM | Q13315 | 1/20 | 0.43 |
| ▸ | TDP1 | Q9NUW8 | 3/20 | 0.42 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.42 |
| ▸ | CCR1 | P32246 | 1/20 | 0.42 |
| ▸ | PKM | P14618 | 1/20 | 0.42 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.42 |
| ▸ | CASP1 | P29466 | 1/20 | 0.42 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.42 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.42 |
| ▸ | PRNP | P04156 | 1/20 | 0.42 |
| ▸ | RXFP1 | Q9HBX9 | 1/20 | 0.42 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.42 |
| ▸ | CHKA | P35790 | 1/20 | 0.41 |
| ▸ | LMNA | P02545 | 1/20 | 0.41 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL21160763 | 0.82 | NR4A2 (0.56) | NR4A2SOS2CYP1A2MAPTGAA | |
| SCHEMBL24420728 | 0.76 | NR4A2 (0.58) | NR4A2SOS2CYP1A2MAPTTDP1 | |
| SCHEMBL8067788 | 0.73 | NR4A2 (0.40) | NR4A2SOS2CYP1A2MAPTTDP1 | |
| SCHEMBL669631 | 0.72 | NR4A2 (0.56) | NR4A2SOS2CYP1A2MAPTGAA | |
| SCHEMBL5275609 | 0.72 | NR4A2 (0.56) | NR4A2SOS2CYP1A2MAPTGAA | |
| SCHEMBL30025652 | 0.72 | CYP3A4 (0.41) | CYP1A2MAPTTDP1KMT2AHSD17B10 | |
| SCHEMBL23535243 | 0.72 | CYP3A4 (0.41) | CYP1A2MAPTTDP1KMT2AHSD17B10 | |
| SCHEMBL23534517 | 0.72 | CYP3A4 (0.41) | CYP1A2MAPTTDP1KMT2AHSD17B10 | |
| SCHEMBL9229271 | 0.72 | NR4A2 (0.51) | NR4A2SOS2CYP1A2MAPTGAA | |
| SCHEMBL14321599 | 0.71 | TSHR (0.41) | MAPTGAATDP1HSD17B10ALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 5 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-6117884-A | 4-substituted quinoline derivatives having fungicidal activity | DAEUBLE JOHN (US) | 2000-09-12 | — | — | US | disclosed |
| CN-1228084-A | 4-substituted quinoline derivatives having fungicidal activity | DOW AGROSCIENCES LLC (US) | 1999-09-08 | — | — | CN | disclosed |
| EP-0925282-A1 | 4-SUBSTITUTED QUINOLINE DERIVATIVES HAVING FUNGICIDAL ACTIVITY | DOWELANCO (US) | 1999-06-30 | — | — | EP | disclosed |
| WO-1998005645-A9 | 4-SUBSTITUTED QUINOLINE DERIVATIVES HAVING FUNGICIDAL ACTIVITY | — | 1998-08-20 | — | — | WO | disclosed |
| WO-1998005645-A1 | 4-SUBSTITUTED QUINOLINE DERIVATIVES HAVING FUNGICIDAL ACTIVITY | DOW AGROSCIENCES LLC (US) | 1998-02-12 | — | — | WO | disclosed |