Predicted protein targets (top 17)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MEN1 | O00255 | 5/20 | 0.47 |
| ▸ | KMT2A | Q03164 | 5/20 | 0.47 |
| ▸ | ALDH1A1 | P00352 | 12/20 | 0.44 |
| ▸ | MAPT | P10636 | 7/20 | 0.44 |
| ▸ | KDM4E | B2RXH2 | 6/20 | 0.43 |
| ▸ | CYP19A1 | P11511 | 1/20 | 0.42 |
| ▸ | LMNA | P02545 | 1/20 | 0.42 |
| ▸ | HTT | P42858 | 2/20 | 0.42 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.41 |
| ▸ | UCHL1 | P09936 | 1/20 | 0.41 |
| ▸ | POLB | P06746 | 2/20 | 0.40 |
| ▸ | THRB | P10828 | 1/20 | 0.40 |
| ▸ | RECQL | P46063 | 1/20 | 0.40 |
| ▸ | HPGD | P15428 | 1/20 | 0.38 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.38 |
| ▸ | GAA | P10253 | 1/20 | 0.38 |
| ▸ | RXFP1 | Q9HBX9 | 1/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7827030 | 0.89 | UCHL1 (0.42) | MEN1KMT2AALDH1A1MAPTLMNA | |
| SCHEMBL5515660 | 0.89 | UCHL1 (0.41) | MEN1KMT2AALDH1A1MAPTKDM4E | |
| SCHEMBL8071924 | 0.87 | CYP19A1 (0.48) | MEN1KMT2AALDH1A1MAPTKDM4E | |
| SCHEMBL7827679 | 0.87 | UCHL1 (0.40) | KMT2AALDH1A1MAPTKDM4ELMNA | |
| SCHEMBL7827515 | 0.87 | KMT2A (0.42) | MEN1KMT2AALDH1A1MAPTCYP19A1 | |
| SCHEMBL7823440 | 0.87 | UCHL1 (0.41) | MEN1KMT2AALDH1A1MAPTCYP19A1 | |
| SCHEMBL8071411 | 0.86 | UCHL1 (0.39) | MEN1KMT2AALDH1A1MAPTUCHL1 | |
| SCHEMBL7816227 | 0.85 | UCHL1 (0.42) | ALDH1A1MAPTKDM4ECYP19A1HTT | |
| SCHEMBL7826821 | 0.85 | UCHL1 (0.40) | MEN1KMT2AALDH1A1MAPTLMNA | |
| SCHEMBL7824948 | 0.85 | MAOB (0.43) | MEN1KMT2AALDH1A1MAPTLMNA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-6093714-A | AN ANTIALLERGENS FOR TREATMENT AND PREVENTION OF BRONCHIAL ASTHMA, ECZEMA, HIVES, ALLERGIC GASTROINTESTINAL TROUBLES, ALLERGIC RHINITIS, ALLERGIC CONJUNCTIVITIS | MEIJI SEIKA KAISHA, LTD. (JP) | 2000-07-25 | — | — | US | disclosed |
| EP-0834512-A1 | TRICYCLIC BENZAZEPINE COMPOUNDS | MEIJI SEIKA KAISHA LTD. (JP) | 1998-04-08 | — | — | EP | disclosed |